A new case of XX-male (XX/XXY mosaic).

Human genetics ·Vol. 39 ·No. 1 ·1977-11-02 ·Pages 131-7

Kaiser P, Gerhard-Ratschow K, Zabel B, Gey W

Abstract

We report a 10-year-old male patients with the predominant karyotype 46,XX. In only one cell of the testis culture a metaphase with 47,XX+G was found. The theories of etiology of XX-males and the reported cases of XX/XXY-mosaics in the literature were discussed.

MeSH Terms

Child Female Humans Male Mosaicism Sex Chromosome Aberrations/diagnosis,pathology Testis/pathology X Chromosome

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Kaiser P

Gerhard-Ratschow K

Zabel B

Gey W

References (22)

22 references, click to expand

Letter: Possible evidence for Xp plus in and XX Male.
Lancet. 1974 Jun 15;1(7868):1223 PMID: 4134689
A clinical and cytogenetical study of three patients with male phenotype and apparent XX sex chromosome constitution.
Acta Endocrinol (Copenh). 1966 May;52(1):91-112 PMID: 4161439
Significance of sex chromosome derived heterochromatin in mammals.
Nature. 1968 Aug 31;219(5157):910-4 PMID: 5673003
Xg groups and sex abnormalities in people of northern European ancestry.
J Med Genet. 1971 Dec;8(4):417-26 PMID: 5149524
[A further case of a male individual with a 46,XX karyotype].
Ann Genet. 1974 Sep;17(3):201-9 PMID: 4548823
XX males: two new cases.
Clin Genet. 1975 May-Jun;7(5):394-9 PMID: 1149308
Leydig cell ultrastructure in an XX male.
J Urol. 1974 Nov;112(5):651-4 PMID: 4421207
Paternal transmission of maleness in XX human beings.
N Engl J Med. 1973 Mar 15;288(11):539-45 PMID: 4685451
An XX male: cytogenetic and endocrine studies.
Clin Genet. 1975 Feb;7(2):155-62 PMID: 1132164
A Klinefelter patient with XX constitution.
Hereditas. 1970;64(1):148-50 PMID: 5525757
X-Y chromosomal interchange in the aetiology of true hermaphroditism and of XX Klinefelter's syndrome.
Lancet. 1966 Aug 27;2(7461):475-6 PMID: 4161595
[Masculinization of XX males (author's transl)].
Humangenetik. 1974;21(3):245-53 PMID: 4847729
Analytic review: nature and origin of males with XX sex chromosomes.
Am J Hum Genet. 1972 Jan;24(1):71-105 PMID: 4622299
[Extended hypothesis of mosaicism as explanation for XX-men].
Humangenetik. 1974 Jul 15;23(2):161-2 PMID: 4848732
Y-chromatin positive cells in the smear preparations of the gonad from a XX male.
Humangenetik. 1975 Nov 6;30(2):193-6 PMID: 1193606
XXY cells in a predominantly XX human male: evidence for cell selection.
Pediatrics. 1966 Dec;38(6):982-5 PMID: 5928728
A casuistic contribution to the XX male problem.
Humangenetik. 1973;17(2):145-54 PMID: 4691148
Infantile XX male: a case report.
Clin Genet. 1976 Oct;10(4):208-13 PMID: 975596
Two XX males in one family and additional observations bearing on the etiology of XX males.
Clin Genet. 1977 Feb;11(2):91-106 PMID: 837567
[Masculin phenotype in a child with a predominant 46, XX clone].
Pediatrie. 1975 Jan-Feb;30(1):73-6 PMID: 1129020
Presence of brightly fluorescent material in testes of XX males.
J Med Genet. 1973 Jun;10(2):170-4 PMID: 4714585
[XX-male-syndrome. Pathogenesis and aspects of diagnostic pitfalls (author's transl)].
Urologe A. 1975 Jul;14(4):182-6 PMID: 1154567

Article Info

Journal

Human genetics

Abbr.

Hum Genet

ISSN

0340-6717

DOI

10.1007/BF00273164

Published

1977-11-02

Pages

131-7

Language

English

Region

Germany

NLM ID

7613873

Subset

External Links

PubMed source DOI: 10.1007/BF00273164 View journal details

Analysis Services

A new case of XX-male (XX/XXY mosaic).

Contact

WeChat Official Account