[XX-male-syndrome. Pathogenesis and aspects of diagnostic pitfalls (author's transl)].

Das XX-Mann-Syndrom: Pathogenese und Beitrag zu den Fehlermöglichkeiten der Diagnose

Der Urologe. Ausg. A ·Vol. 14 ·No. 4 ·1975-07-00 ·Pages 182-6

Rehder H, Brühl P, Seth PK

Abstract

A boy with XX-karyotype displayed classical features of Klinefelter's syndrome. In the nuclei of hair root cells Barr-bodies were present as well as brightly fluorescent (F-)bodies resembling closely a Y-body. In lymphocyte metaphases, however, this F-body of the interphase nuclei corresponded to a brightly fluorescent segment of the short arm of a D15-chromosome was found in the father's karyotype. This case does not give convincing support to any of the theories suggested in the etiology of the XX-male phenomenon.

MeSH Terms

Adolescent Chromosomes/analysis Chromosomes, Human, 13-15 Diagnosis, Differential Diagnostic Errors Disorders of Sex Development/diagnosis Gynecomastia Humans Hypospadias/surgery Karyotyping Klinefelter Syndrome/diagnosis Leydig Cells/pathology Male Sex Chromatin/analysis Sex Chromosome Aberrations Sex Chromosomes Testosterone/blood Translocation, Genetic

Chemicals

Testosterone

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Rehder H

Brühl P

Seth P K

Article Info

Journal

Der Urologe. Ausg. A

Abbr.

Urologe A

ISSN

0340-2592

Published

1975-07-00

Pages

182-6

Language

ger

Region

Germany

NLM ID

1304110

Subset

External Links

PubMed source View journal details

Analysis Services

[XX-male-syndrome. Pathogenesis and aspects of diagnostic pitfalls (author's transl)].

Contact

WeChat Official Account