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PMID: 6946272 Published · ppublish English Comparative Study Journal Article Research Support, Non-U.S. Gov't

Usage of the three termination codons: compilation and analysis of the known eukaryotic and prokaryotic translation termination sequences.

Molecular & general genetics : MGG ·Vol. 182 ·No. 3 ·1981-00-00 ·Pages 430-9

Kohli J, Grosjean H

Abstract

The published translation termination sequences have been compiled and analysed to aid the interpretation of experiments on termination codon usage in the Xenopus oocyte (Bienz et al. 1981). There are significant differences between prokaryotes and eukaryotes concerning the usage of the three termination codons and of tandem stops. In addition viruses show termination strategies that differ from those of their hosts. Preferred context sequences flanking termination codons are described. Contexts vary within the last codon according to the nature of the termination codon, but are uniform within the first triplet following the terminators.

MeSH Terms
Animals Base Sequence Cell Physiological Phenomena Codon DNA, Mitochondrial/genetics Eukaryotic Cells/physiology Humans Peptide Chain Termination, Translational Prokaryotic Cells/physiology RNA, Messenger/genetics
Chemicals
Codon DNA, Mitochondrial RNA, Messenger
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Kohli J
Grosjean H
References (16)
16 references, click to expand
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Article Info
Journal
Molecular & general genetics : MGG
Abbr.
Mol Gen Genet
ISSN
0026-8925
Published
1981-00-00
Pages
430-9
Language
English
Region
Germany
NLM ID
0125036
Subset
IM
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