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PMID: 6870225 Published · ppublish English Journal Article

Transferable resistance to clindamycin, erythromycin, and tetracycline in Clostridium difficile.

Antimicrobial agents and chemotherapy ·Vol. 23 ·No. 5 ·1983-05-00 ·Pages 784-6

Wüst J, Hardegger U

Abstract

Resistance to clindamycin, erythromycin, and streptogramins in Clostridium difficile could be transferred to a susceptible strain by mixed culture at low frequencies (1 x 10(-8) to 4 - 10(-8) per donor cell). Transfer of tetracycline resistance occurred at frequencies of 3 x 10(-7) to 5 x 10(-7). No plasmid DNA involved in these transfers could be detected.

MeSH Terms
Anti-Bacterial Agents/pharmacology Clindamycin/pharmacology Clostridium/drug effects Conjugation, Genetic Drug Resistance, Microbial Erythromycin/pharmacology Tetracycline/pharmacology
Chemicals
Anti-Bacterial Agents Clindamycin Erythromycin Tetracycline
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Wüst J
Hardegger U
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22 references, click to expand
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Article Info
Journal
Antimicrobial agents and chemotherapy
Abbr.
Antimicrob Agents Chemother
ISSN
0066-4804
DOI
10.1128/AAC.23.5.784
Published
1983-05-00
Pages
784-6
Language
English
Region
United States
NLM ID
0315061
PMCID
PMC184818
Subset
IM
External Links
PubMed source DOI: 10.1128/AAC.23.5.784 PMC Full Text View journal details
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