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PMID: 6800879 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Post-translation modification of xanthine dehydrogenase in a natural population of Drosophila melanogaster.

Genetics ·Vol. 98 ·No. 4 ·1981-08-00 ·Pages 817-31

Johnson G, Finnerty V, Hartl D

Abstract

Second chromosomes of D. melanogaster were isolated from a single natural population, and 40 were analyzed by gel-sieving electrophoresis for the presence of polymorphic loci on chromosome 2 that act to modify xanthine dehydrogenase and/or aldehyde oxidase, whose structural genes map to chromosome 3. Clear evidence of polymorphism for one or more xanthine dehydrogenase modifier loci was obtained.

MeSH Terms
Aldehyde Oxidoreductases/genetics Animals Drosophila melanogaster/genetics Genes Genetic Variation Ketone Oxidoreductases/genetics Polymorphism, Genetic Protein Biosynthesis Protein Precursors/metabolism Xanthine Dehydrogenase/genetics
Chemicals
Protein Precursors Xanthine Dehydrogenase Aldehyde Oxidoreductases Ketone Oxidoreductases
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Johnson G
Finnerty V
Hartl D
References (6)
6 references, click to expand
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    Proc Natl Acad Sci U S A. 1974 May;71(5):1808-10 PMID: 4525464
  2. The study of genic variation by electrophoretic and heat denaturation techniques at the octanol dehydrogenase locus in members of the Drosophila virilis group.
    Genetics. 1975 Jul;(3):637-50 PMID: 1232029
  3. Further evidence of thermostability variation within electrophoretic mobility classes of enzymes.
    Biochem Genet. 1976 Apr;14(3-4):383-7 PMID: 822839
  4. Linkage disequilibrium between functionally related enzyme loci of Drosophila mojavensis.
    Can J Genet Cytol. 1976 Jun;18(2):245-54 PMID: 990995
  5. Gene expression in Drosophila: post-translational modification of aldehyde oxidase and xanthine dehydrogenase.
    Mol Gen Genet. 1979 Apr 17;172(1):37-43 PMID: 286873
  6. Genic heterogeneity within electrophoretic "alleles" and the pattern of variation among loci in Drosophila pseudoobscura.
    Genetics. 1979 Dec;93(4):997-1018 PMID: 546677
Article Info
Journal
Genetics
Abbr.
Genetics
ISSN
0016-6731
DOI
10.1093/genetics/98.4.817
Published
1981-08-00
Pages
817-31
Language
English
Region
United States
NLM ID
0374636
PMCID
PMC1214477
Subset
IM
Grants
NIGMS NIH HHS · GM-23504 · United States
NIGMS NIH HHS · GM-23736 · United States
External Links
PubMed source DOI: 10.1093/genetics/98.4.817 PMC Full Text View journal details
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