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PMID: 6765418 Published · ppublish English Clinical Trial Journal Article

Activities of amoxicillin and clavulanic acid combinations against urinary tract infections.

Antimicrobial agents and chemotherapy ·Vol. 22 ·No. 2 ·1982-08-00 ·Pages 346-9

Crokaert F, van der Linden MP, Yourassowsky E

Abstract

Urinary tract infection caused by beta-lactamase-producing bacteria were treated with 500 mg of amoxicillin three times daily plus either 250 or 125 mg of clavulanic acid three times daily. The overall cure rate was 63.6%, 77.7% with the high dose of clavulanic acid and 53.8% with the low dose. Gastrointestinal intolerance was common in the high-dose clavulanic acid regimen.

MeSH Terms
Administration, Oral Aged Amoxicillin/administration & dosage Bacterial Infections/drug therapy Clavulanic Acid Clavulanic Acids/administration & dosage,adverse effects Clinical Trials as Topic Drug Therapy, Combination Drug Tolerance Female Humans Male Middle Aged Urinary Tract Infections/drug therapy
Chemicals
Clavulanic Acids Clavulanic Acid Amoxicillin
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Crokaert F
van der Linden M P
Yourassowsky E
References (16)
16 references, click to expand
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Article Info
Journal
Antimicrobial agents and chemotherapy
Abbr.
Antimicrob Agents Chemother
ISSN
0066-4804
DOI
10.1128/AAC.22.2.346
Published
1982-08-00
Pages
346-9
Language
English
Region
United States
NLM ID
0315061
PMCID
PMC183740
Subset
IM
External Links
PubMed source DOI: 10.1128/AAC.22.2.346 PMC Full Text View journal details
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