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PMID: 6654334 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Chromosomal localization of a human myosin heavy-chain gene by in situ hybridization.

Human genetics ·Vol. 65 ·No. 2 ·1983-00-00 ·Pages 195-7

Rappold GA, Vosberg HP

Abstract

A cloned rabbit heart muscle myosin heavy-chain cDNA was hybridized in situ with human metaphase chromosomes. The probe was known to have sequence homology with human genomic heavy-chain DNA. Only one site in the human haploid karyotype was labeled with the cDNA, and this site was found on the short arm of chromosome 17. The localization of autoradiographic grains suggests a subregional assignment of the myosin heavy-chain locus to 17p 1,2-pter.

MeSH Terms

Animals Chromosomes, Human, 16-18 DNA/genetics Humans Metaphase Myosins/genetics Nucleic Acid Hybridization Rabbits

Chemicals

DNA Myosins

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Rappold G A

Vosberg H P

References (17)

17 references, click to expand

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Article Info

Journal

Human genetics

Abbr.

Hum Genet

ISSN

0340-6717

DOI

10.1007/BF00286663

Published

1983-00-00

Pages

195-7

Language

English

Region

Germany

NLM ID

7613873

Subset

External Links

PubMed source DOI: 10.1007/BF00286663 View journal details

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Chromosomal localization of a human myosin heavy-chain gene by in situ hybridization.

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