Hidden electrophoretic variation at the xanthine dehydrogenase locus in a natural population of Drosophila melanogaster.

Genetics ·Vol. 104 ·No. 2 ·1983-06-00 ·Pages 301-15

Buchanan BA, Johnson DL

Abstract

Sixty-two isochromosomal lines of D. melanogaster were screened for cryptic electrophoretic variation at the xanthine dehydrogenase (XDH) locus. Sequential polyacrylamide vertical slab gel electrophoresis was performed using four electrophoretic criteria. A total of 15 classes of electromorphs were revealed. D. melanogaster appears to exhibit as much polymorphism at this locus as other extensively studied Drosophila species.--No evidence for loci on the X or second chromosomes which modified XDH mobility was found. Six of the electromorphs were mapped to the Xdh (ry) structural locus. Eight of the remaining nine classes exhibited mobility variation consistent with structural variation at the Xdh locus. The final class exhibited aberrant patterns and is under further study.

MeSH Terms

Animals Crosses, Genetic Drosophila melanogaster/enzymology,genetics Electrophoresis, Polyacrylamide Gel Female Genetic Variation Ketone Oxidoreductases/genetics Male Recombination, Genetic Xanthine Dehydrogenase/genetics

Chemicals

Xanthine Dehydrogenase Ketone Oxidoreductases

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Buchanan B A

Johnson D L

References (19)

19 references, click to expand

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Article Info

Journal

Genetics

Abbr.

Genetics

ISSN

0016-6731

DOI

10.1093/genetics/104.2.301

Published

1983-06-00

Pages

301-15

Language

English

Region

United States

NLM ID

0374636

PMCID

PMC1202078

Subset

External Links

PubMed source DOI: 10.1093/genetics/104.2.301 PMC Full Text View journal details

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Hidden electrophoretic variation at the xanthine dehydrogenase locus in a natural population of Drosophila melanogaster.

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