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PMID: 6280146 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Repetitive DNA sequences in the human corticotropin-beta-lipotrophin precursor gene region: Alu family members.

Nucleic acids research ·Vol. 10 ·No. 5 ·1982-03-11 ·Pages 1471-9

Tsukada T, Watanabe Y, Nakai Y, Imura H, Nakanishi S, Numa S

Abstract

Repetitive DNA sequences in the human corticotropin-beta-lipotropin precursor gene region have been studied by blot hybridization analysis and DNA sequencing. Six repetitive sequences are present in this gene region; five of them are Alu family members with an approximate length of 300 base pairs, and the other consists of a portion of an Alu family sequence. Two of these Alu family members are located in the 5'-flanking region of the gene, and the remaining four within the intervening sequences. These Alu family sequences constitute inverted repeats in the intervening sequences as well as in the 5'-flanking region of the gene.

MeSH Terms
Adrenocorticotropic Hormone/genetics Base Composition DNA/genetics DNA Restriction Enzymes Genes Humans Repetitive Sequences, Nucleic Acid beta-Lipotropin/genetics
Chemicals
Adrenocorticotropic Hormone DNA beta-Lipotropin DNA Restriction Enzymes
Authors & Affiliations
6 authors, click to expand affiliations / ORCID
Tsukada T
Watanabe Y
Nakai Y
Imura H
Nakanishi S
Numa S
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27 references, click to expand
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Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
0305-1048
DOI
10.1093/nar/10.5.1471
Published
1982-03-11
Pages
1471-9
Language
English
Region
England
NLM ID
0411011
PMCID
PMC320543
Subset
IM
Databases
GENBANK
K00059, K00060, K00061, K00062, K00063, K00064
External Links
PubMed source DOI: 10.1093/nar/10.5.1471 PMC Full Text View journal details
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