Evidence that the genome of hepatitis A virus consists of single-stranded RNA.

Journal of virology ·Vol. 37 ·No. 1 ·1981-01-00 ·Pages 473-7

Coulepis AG, Tannock GA, Locarnini SA, Gust ID

Abstract

Nucleic acid was extracted from purified hepatitis A virus, radiolabeled with 125I, and shown to consist of single-stranded RNA which sediments at 35S and contains sequences of polyadenylic acid. These findings are consistent with hepatitis A virus being a member of the genus Enterovirus within the family Picornaviridae.

MeSH Terms

Centrifugation, Density Gradient Chromatography, Affinity Hepatovirus/classification,genetics RNA, Viral/genetics,isolation & purification

Chemicals

RNA, Viral

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Coulepis A G

Tannock G A

Locarnini S A

Gust I D

References (22)

22 references, click to expand

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Article Info

Journal

Journal of virology

Abbr.

J Virol

ISSN

0022-538X

DOI

10.1128/JVI.37.1.473-477.1981

Published

1981-01-00

Pages

473-7

Language

English

Region

United States

NLM ID

0113724

PMCID

PMC171023

Subset

External Links

PubMed source DOI: 10.1128/JVI.37.1.473-477.1981 PMC Full Text View journal details

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Evidence that the genome of hepatitis A virus consists of single-stranded RNA.

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