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PMID: 6251236 Published · ppublish English Comparative Study Journal Article

Polyoma virus DNA: Sequence from the late region that specifies the leader sequence for late mRNA and codes for VP2, VP3, and the N-terminus of VP1.

Journal of virology ·Vol. 33 ·No. 2 ·1980-02-00 ·Pages 606-18

Arrand JR, Soeda E, Walsh JE, Smolar N, Griffin BE

Abstract

The DNA sequence of part of the late region of the polyoma virus genome is presented. This sequence of 1,348 nucleotide pairs encompasses the leader region for late mRNA and the coding sequence for the two minor capsid proteins VP2 and VP3. The coding sequence for the N-terminus of the major capsid protein overlaps the C-terminus of VP2/VP3 by 32 nucleotide pairs. From the DNA sequence the sizes and sequences of VP2 and VP3 could be predicted. Potential splicing signals for the processing of late mRNA's could be identified. Comparisons are made between the sequence of polyoma virus DNA and corresponding regions of simian virus 40 DNA.

MeSH Terms
Amino Acid Sequence Base Sequence Capsid/genetics DNA Restriction Enzymes DNA, Viral/analysis Polyomavirus/genetics RNA, Messenger/genetics RNA, Viral/genetics Simian virus 40/genetics Viral Proteins/genetics
Chemicals
DNA, Viral RNA, Messenger RNA, Viral Viral Proteins DNA Restriction Enzymes
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Arrand J R
Soeda E
Walsh J E
Smolar N
Griffin B E
References (48)
48 references, click to expand
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Article Info
Journal
Journal of virology
Abbr.
J Virol
ISSN
0022-538X
DOI
10.1128/JVI.33.2.606-618.1980
Published
1980-02-00
Pages
606-18
Language
English
Region
United States
NLM ID
0113724
PMCID
PMC288585
Subset
IM
Databases
GENBANK
J02288, J02290, J02291, J02292, K00932, K00997, K01041, K01071, K01072, V01117, V01147
External Links
PubMed source DOI: 10.1128/JVI.33.2.606-618.1980 PMC Full Text View journal details
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