The activity of vancomycin and teicoplanin alone and in combination with gentamicin or ampicillin against Streptococcus faecalis.

European journal of clinical microbiology ·Vol. 3 ·No. 5 ·1984-10-00 ·Pages 436-8

Chen HY, Williams JD

Abstract

The in vitro activities of vancomycin and teicoplanin against 56 strains of Streptococcus faecalis were compared. Killing curves showed that vancomycin and teicoplanin were bacteriostatic and that synergy was achieved when each was combined with gentamicin. The bactericidal activity displayed by 4 mg/l of ampicillin against Streptococcus faecalis was antagonized by 4 mg/l of vancomycin and 0.5 mg/l of teicoplanin respectively.

MeSH Terms

Ampicillin/administration & dosage,antagonists & inhibitors,pharmacology Anti-Bacterial Agents/administration & dosage,pharmacology Drug Synergism Enterococcus faecalis/drug effects Gentamicins/administration & dosage,pharmacology Glycopeptides/administration & dosage,pharmacology Teicoplanin Vancomycin/administration & dosage,pharmacology

Chemicals

Anti-Bacterial Agents Gentamicins Glycopeptides Teicoplanin Vancomycin Ampicillin

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Chen H Y

Williams J D

References (7)

7 references, click to expand

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Comparison of the in vitro activities of teichomycin A2 and vancomycin against staphylococci and enterococci.
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In vitro activity of teichomycin A 2 in comparison with penicillin and vancomycin against gram-positive cocci.
Eur J Clin Microbiol. 1982 Oct;1(5):278-81 PMID: 6223812
Studies on antibiotic syngerism against enterococci. II. Effect of various antibiotics on the uptake of 14 C-labeled streptomycin by enterococci.
J Clin Invest. 1971 Dec;50(12):2580-4 PMID: 5001959
The killing effects of cefathiamidine or ampicillin alone and in combination with gentamicin against enterococci.
J Antimicrob Chemother. 1983 Jul;12(1):19-26 PMID: 6413484
Synergism of vancomycin-gentamicin and vancomycin-streptomycin against enterococci.
Antimicrob Agents Chemother. 1973 Aug;4(2):120-4 PMID: 4790933
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Nature. 1978 Jan 19;271(5642):223-5 PMID: 622161

Article Info

Journal

European journal of clinical microbiology

Abbr.

Eur J Clin Microbiol

ISSN

0722-2211

DOI

10.1007/BF02017366

Published

1984-10-00

Pages

436-8

Language

English

Region

Germany

NLM ID

8219582

Subset

External Links

PubMed source DOI: 10.1007/BF02017366

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The activity of vancomycin and teicoplanin alone and in combination with gentamicin or ampicillin against Streptococcus faecalis.

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