In vitro activity of teichomycin A 2 in comparison with penicillin and vancomycin against gram-positive cocci.

European journal of clinical microbiology ·Vol. 1 ·No. 5 ·1982-10-00 ·Pages 278-81

Bauernfeind A, Petermüller C

Abstract

Teichomycin A2, a glycopeptide antibiotic from Actinoplanes teichomyceticus, was tested for its in vitro activity against 190 gram-positive cocci under variable test conditions. Minimum inhibitory concentrations were fairly insensitive to both changes of inoculum size and pH, but were higher on agar than in broth. Teichomycin was about as active as vancomycin against Staphylococcus aureus (both methicillin resistant and sensitive strains), slightly inferior to vancomycin against Staphylococcus epidermidis, and distinctly more active against Streptococcus faecalis.

MeSH Terms

Anti-Bacterial Agents/pharmacology Enterococcus faecalis/drug effects Methicillin/pharmacology Microbial Sensitivity Tests Penicillins/pharmacology Staphylococcus/drug effects Staphylococcus aureus/drug effects Teicoplanin Vancomycin/pharmacology

Chemicals

Anti-Bacterial Agents Penicillins Teicoplanin Vancomycin Methicillin

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Bauernfeind A

Petermüller C

References (13)

13 references, click to expand

Comparison of the in vitro activities of teichomycin A2 and vancomycin against staphylococci and enterococci.
Antimicrob Agents Chemother. 1982 Mar;21(3):504-5 PMID: 6213192
A new type of penicillin resistance of Staphylococcus aureus.
Lancet. 1977 Feb 26;1(8009):443-7 PMID: 65561
Lysostaphin disk test for routine presumptive identification of staphylococci.
J Clin Microbiol. 1981 Jun;13(6):1023-5 PMID: 7019233
Variable tolerance of a clinical isolate of Staphylococcus epidermidis from an infected hydrocephalus shunt for several beta-lactam antibiotics, vancomycin and fosfomycin.
Chemotherapy. 1981;27(6):432-43 PMID: 7297172
[Resistance of methicillin-resistant staphylococci to new cephalosporin antibiotics (author's transl)].
Infection. 1980;8(4):165-70 PMID: 7298199
Piperacillin, a new penicillin active against many bacteria resistant to other penicillins.
Antimicrob Agents Chemother. 1978 Mar;13(3):358-67 PMID: 122519
Antibiotic resistance plasmids of Staphylococcus aureus and their clinical importance.
Bacteriol Rev. 1975 Mar;39(1):1-32 PMID: 1091256
[Pathogenic spectrum for septicemia, 1974-1980].
Dtsch Med Wochenschr. 1981 Apr 3;106(14):445-6 PMID: 7215170
A simple test system for the separation of staphylococci from micrococci.
J Clin Microbiol. 1975 Mar;1(3):337-8 PMID: 1100662
Teichomycins, new antibiotics from Actinoplanes teichomyceticus Nov. Sp. I. Description of the producer strain, fermentation studies and biological properties.
J Antibiot (Tokyo). 1978 Apr;31(4):276-83 PMID: 659325
Teichomycins, new antibiotics from Actinoplanes teichomyceticus nov. sp. II. Extraction and chemical characterization.
J Antibiot (Tokyo). 1978 Mar;31(3):170-7 PMID: 649512
Methicillin-resistant Staphylococcus aureus--United States.
MMWR Morb Mortal Wkly Rep. 1981 Nov 20;30(45):557-9 PMID: 6795434
Emergence of gentamicin- and methicillin-resistant Staphylococcus aureus strains in New York City hospitals.
J Clin Microbiol. 1981 Apr;13(4):754-9 PMID: 6908898

Article Info

Journal

European journal of clinical microbiology

Abbr.

Eur J Clin Microbiol

ISSN

0722-2211

DOI

10.1007/BF02019971

Published

1982-10-00

Pages

278-81

Language

English

Region

Germany

NLM ID

8219582

Subset

External Links

PubMed source DOI: 10.1007/BF02019971

Analysis Services

In vitro activity of teichomycin A 2 in comparison with penicillin and vancomycin against gram-positive cocci.

Contact

WeChat Official Account