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PMID: 621787 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Mutator and antimutator phenotypes of suppressed amber mutants in genes 32, 41, 44, 45, and 62 in bacteriophage T4.

Journal of virology ·Vol. 25 ·No. 1 ·1978-01-00 ·Pages 73-7

Watanabe SM, Goodman MF

Abstract

Bacteriophage T4 genes 32, 41, 44, 45, 56, and 62 are essential to DNA replication. Amber mutants (suppressed by su+1, su+2, or su+3 bacteria) in these genes were examined for any mutator or antimutator effects on the reversion of a transition mutation. In every case except for mutations in gene 56, elevated or lowered error frequencies were observed. These results indicate the importance of all of the replicative proteins in the determination of error frequency.

MeSH Terms
Coliphages/genetics DNA Replication DNA, Viral/genetics Genes, Viral Mutation Phenotype Suppression, Genetic
Chemicals
DNA, Viral
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Watanabe S M
Goodman M F
References (23)
23 references, click to expand
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Article Info
Journal
Journal of virology
Abbr.
J Virol
ISSN
0022-538X
DOI
10.1128/JVI.25.1.73-77.1978
Published
1978-01-00
Pages
73-7
Language
English
Region
United States
NLM ID
0113724
PMCID
PMC353902
Subset
IM
External Links
PubMed source DOI: 10.1128/JVI.25.1.73-77.1978 PMC Full Text View journal details
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