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PMID: 6111558 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Regulation of glutamine synthetase by regulatory protein PII in Klebsiella aerogenes mutants lacking adenylyltransferase.

Journal of bacteriology ·Vol. 146 ·No. 2 ·1981-05-00 ·Pages 740-5

Reuveny Z, Foor F, Magasanik B

Abstract

A mutation of Klebsiella aerogenes causing production of an altered PII regulatory protein which stimulates overadenylylation of glutamine synthetase and also prevents its derepression was combined with mutations abolishing the activity of adenylyltransferase. The results support the idea that PII plays a role in the regulation of the level of glutamine synthetase which is independent of its interaction with adenylyltransferase.

MeSH Terms

Bacterial Proteins/genetics,physiology Glutamate-Ammonia Ligase/biosynthesis Klebsiella pneumoniae/enzymology,genetics Mutation Nucleotidyltransferases/metabolism PII Nitrogen Regulatory Proteins

Chemicals

Bacterial Proteins PII Nitrogen Regulatory Proteins PIID regulatory protein, Bacteria Nucleotidyltransferases glutamine-synthetase adenylyltransferase Glutamate-Ammonia Ligase

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Reuveny Z

Foor F

Magasanik B

References (25)

25 references, click to expand

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Article Info

Journal

Journal of bacteriology

Abbr.

J Bacteriol

ISSN

0021-9193

DOI

10.1128/jb.146.2.740-745.1981

Published

1981-05-00

Pages

740-5

Language

English

Region

United States

NLM ID

2985120R

PMCID

PMC217020

Subset

Grants

NIADDK NIH HHS · AM-13894 · United States

NIGMS NIH HHS · GM-07446 · United States

External Links

PubMed source DOI: 10.1128/jb.146.2.740-745.1981 PMC Full Text View journal details

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Regulation of glutamine synthetase by regulatory protein PII in Klebsiella aerogenes mutants lacking adenylyltransferase.

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