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PMID: 6102985 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S.

Regulation of nitrogen metabolism in glutamine auxotrophs of Klebsiella pneumoniae.

Journal of bacteriology ·Vol. 142 ·No. 1 ·1980-04-00 ·Pages 99-110

Leonardo JM, Goldberg RB

Abstract

We examined the regulation of nitrogen metabolism in four classes (glnA, glnB, glnF, and glnG) of Gln- auxotrophs of Klebsiella pneumoniae. These studies indicate that glutamine synthetase does not directly mediate the physiological response to NH4+ in this organism. We present evidence suggesting that the effect of NH4+ on the expression of genes involved in nitrogen metabolism involves the products of the glnF and glnG genes.

MeSH Terms
Chromosome Mapping Genes Glutamate-Ammonia Ligase/metabolism Klebsiella pneumoniae/enzymology,genetics,metabolism Mutation Nitrogen/metabolism Quaternary Ammonium Compounds/pharmacology Suppression, Genetic
Chemicals
Quaternary Ammonium Compounds Glutamate-Ammonia Ligase Nitrogen
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Leonardo J M
Goldberg R B
References (46)
46 references, click to expand
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Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/jb.142.1.99-110.1980
Published
1980-04-00
Pages
99-110
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC293910
Subset
IM
External Links
PubMed source DOI: 10.1128/jb.142.1.99-110.1980 PMC Full Text View journal details
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