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PMID: 5662010 Published · ppublish English Journal Article

Cellular immunity in vaccinia infection of mice. Anti-thymocyte serum effects on primary and secondary responsiveness.

The Journal of experimental medicine ·Vol. 128 ·No. 1 ·1968-07-01 ·Pages 121-32

Hirsch MS, Nahmias AJ, Murphy FA, Kramer JH

Abstract

Rabbit anti-mouse thymocyte serum suppressed host cell-mediated responsiveness to intravenously administered vaccinia virus, thereby augmenting the morbidity and mortality of this infection. It did not affect either humoral antibody or interferon production in response to vaccinia virus. No effects were noted on primary or secondary immunity to intracerebral virus inoculation.

MeSH Terms
Animals Antibodies/analysis Antibody Formation Hemagglutination Inhibition Tests Immune Sera Injections, Intraperitoneal Injections, Intravenous Interferons/biosynthesis Male Mice Thymus Gland/cytology,immunology Vaccinia/immunology
Chemicals
Antibodies Immune Sera Interferons
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Hirsch M S
Nahmias A J
Murphy F A
Kramer J H
References (26)
26 references, click to expand
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Article Info
Journal
The Journal of experimental medicine
Abbr.
J Exp Med
ISSN
0022-1007
DOI
10.1084/jem.128.1.121
Published
1968-07-01
Pages
121-32
Language
English
Region
United States
NLM ID
2985109R
PMCID
PMC2138509
Subset
IM
External Links
PubMed source DOI: 10.1084/jem.128.1.121 PMC Full Text View journal details
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