Home LiteratureArticle Details
PMID: 5308064 Published · ppublish English Journal Article

Cells involved in the immune response. XVI. The response of immune rabbit cells to phytohemagglutinin, antigen, and goat anti-rabbit immunoglobulin antiserum.

The Journal of experimental medicine ·Vol. 131 ·No. 1 ·1970-01-01 ·Pages 119-31

Daguillard F, Richter M

Abstract

There exists in the rabbit a population of lymphocytes carrying immunoglobulin-like receptors on their surface. These receptors interact with antigen and with anti-immunoglobulin antibodies and appear to mediate the recognition process leading to the humoral immune response. There exists in the rabbit a second population of lymphocytes capable of reacting with phytohemagglutinin. This population of lymphocytes is different from the one capable of reacting with soluble protein antigens or anti-immunoglobulin antiserum and is probably involved in the mediation of cellular immunity.

MeSH Terms
Animals Antibodies, Anti-Idiotypic Antibody Formation Antigens Culture Techniques Goats Humans Immune Sera Lymph Nodes/immunology Lymphocytes/drug effects,immunology Lymphoid Tissue/immunology Rabbits Serum Albumin Spleen/immunology Tritium
Chemicals
Antibodies, Anti-Idiotypic Antigens Immune Sera Serum Albumin Tritium
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Daguillard F
Richter M
References (17)
17 references, click to expand
  1. Cells involved in the immune response. IV. The response of normal and immune rabbit bone marrow and lymphoid tissue lymphocytes to antigens in vitro.
    J Exp Med. 1968 Nov 1;128(5):1099-128 PMID: 4176224
  2. Effect of bursectomy and thymectomy on the responses of chicken peripheral blood lymphocytes to phytohaemagglutinin.
    Nature. 1968 Oct 19;220(5164):293-5 PMID: 5684863
  3. Congenital aplasia of the thymus gland (DiGeorge's syndrome).
    N Engl J Med. 1968 Dec 12;279(24):1295-301 PMID: 4177112
  4. Antibody synthesis by blastoid cells transformed in vitro from rabbit blood lymphocytes.
    Scand J Haematol. 1968;5(3):171-8 PMID: 5708118
  5. Antigen-induced cell proliferation in cultures from antibody-deficient chickens.
    J Immunol. 1969 Apr;102(4):1079-83 PMID: 4181247
  6. The relationship between lymphocyte transformation and immune response.
    Immunology. 1969 Mar;16(3):381-6 PMID: 5770385
  7. Apparent dissociation of antigen responsiveness and antibody production by human small lymphocytes in culture.
    Clin Exp Immunol. 1969 Jan;4(1):55-63 PMID: 5786813
  8. Cells involved in the immune response. XII. The differing responses of normal rabbit lymphoid cells to phytohemagglutinin, goat anti-rabbit immunoglobulin antiserum and allogeneic and xenogeneic lymphocytes.
    J Exp Med. 1969 Nov 1;130(5):1187-208 PMID: 5307485
  9. The relationship between lymphocyte transformation and immune responses. II. Correlations between transformation and humoral and cellular immune responses.
    Clin Exp Immunol. 1969 Jul;5(1):155-61 PMID: 4244245
  10. AN IN VITRO SYSTEM FOR THE STUDY OF THE MECHANISM OF ANTIGENIC STIMULATION IN THE SECONDARY RESPONSE.
    Immunology. 1964 Jan;7:40-53 PMID: 14113075
  11. THE SIGNIFICANCE OF THE PROTEIN CARRIER IN THE STIMULATION OF DNA SYNTHESIS BY HAPTEN-PROTEIN CONJUGATES IN THE SECONDARY RESPONSE.
    Immunology. 1964 Jan;7:54-64 PMID: 14113076
  12. Lymphocyte studies in congenital thymic dysplasia: The one-way stimulation test.
    J Pediatr. 1968 Feb;72(2):177-85 PMID: 5635802
  13. The effect of phytohaemagglutinin and other lymphocyte mitogens on immunoglobulin synthesis by human peripheral blood lymphocytes in vitro.
    Clin Exp Immunol. 1968 Jun;3(5):393-412 PMID: 4173924
  14. Effect of lymphocyte stimulants on specific antibody synthesis in vitro.
    Nature. 1968 Aug 31;219(5157):975-8 PMID: 4175122
  15. The effects of antigens and of phytohemagglutinin on rabbit spleen cell suspensions.
    J Exp Med. 1966 Oct 1;124(4):621-34 PMID: 4162447
  16. The mitotic response of thymus-derived cells to antigenic stimulus.
    Transplantation. 1966 Jul;4(4):438-51 PMID: 5967867
  17. Specificity of cellular immune responses. Antigen concentration dependence of stimulation of DNA synthesis in vitro by specifically sensitized cells, as an expression of the binding characteristics of cellular antibody.
    J Exp Med. 1968 Jan 1;127(1):25-42 PMID: 4864671
Article Info
Journal
The Journal of experimental medicine
Abbr.
J Exp Med
ISSN
0022-1007
Published
1970-01-01
Pages
119-31
Language
English
Region
United States
NLM ID
2985109R
PMCID
PMC2138768
Subset
IM
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com