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PMID: 5289029 Published · ppublish English Journal Article

The nucleotide sequence at the 5'-terminus of the Q RNA minus trand.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 67 ·No. 2 ·1970-10-00 ·Pages 921-8

Goodman HM, Billeter MA, Hindley J, Weissmann C

Abstract

The sequence of the first 52 nucleotides at the 5'-end of the Qbeta minus strand has been determined and found to be complementary in an antiparallel fashion to the 3'-terminal region of the Qbeta plus strand. There are few similarities between the corresponding sequences of Qbeta plus and minus strands; however, both have a hydrogen-bonded loop close to the 5'-end. The sequence of the 3'-terminal region of the plus strand was deduced: there are no termination signals within the last 32 nucleotides. A notable homology exists between the 3'-ends of Qbeta and R17 RNA.

MeSH Terms
Adenine Nucleotides/metabolism Autoradiography Bacteriophages/chemistry Base Sequence Cytosine Nucleotides/metabolism Electrophoresis Guanine Nucleotides/metabolism Methods Nucleotides/analysis Pancreas/chemistry RNA Nucleotidyltransferases/metabolism RNA, Viral/analysis,biosynthesis Ribonucleases/metabolism Templates, Genetic Uracil Nucleotides/metabolism
Chemicals
Adenine Nucleotides Cytosine Nucleotides Guanine Nucleotides Nucleotides RNA, Viral Uracil Nucleotides RNA Nucleotidyltransferases Ribonucleases
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Goodman H M
Billeter M A
Hindley J
Weissmann C
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39 references, click to expand
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Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
DOI
10.1073/pnas.67.2.921
Published
1970-10-00
Pages
921-8
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC283293
Subset
IM
External Links
PubMed source DOI: 10.1073/pnas.67.2.921 PMC Full Text View journal details
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