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PMID: 4882370 Published · ppublish English Journal Article

Translation of the genetic message.

Die Naturwissenschaften ·Vol. 55 ·No. 11 ·1968-11-00 ·Pages 505-14

Ochoa S

Abstract

暂无摘要

MeSH Terms
Amino Acids/metabolism Bacterial Proteins/biosynthesis Binding Sites Cell-Free System Escherichia coli/cytology,metabolism Formates/metabolism Genetic Code Genetics, Microbial Guanine Nucleotides/metabolism Lysine/metabolism Magnesium/metabolism Methionine/metabolism Molecular Biology Peptide Biosynthesis Polynucleotides/metabolism Puromycin/pharmacology RNA, Messenger/metabolism RNA, Transfer/metabolism Ribosomes/metabolism
Chemicals
Amino Acids Bacterial Proteins Formates Guanine Nucleotides Polynucleotides RNA, Messenger Puromycin RNA, Transfer Methionine Magnesium Lysine
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Ochoa S
References (79)
79 references, click to expand
  1. Direction of reading of the genetic message. II.
    Proc Natl Acad Sci U S A. 1966 Jan;55(1):141-7 PMID: 5328637
  2. FRACTIONATION OF THE RIBOSOMAL PROTEIN FROM ESCHERICHIA COLI.
    J Mol Biol. 1964 Nov;10:319-36 PMID: 14235590
  3. GTP-stimulated binding of initiator-tRNA to ribosomes directed by f2 bacteriophage RNA.
    Nature. 1967 Dec 16;216(5120):1072-6 PMID: 6075248
  4. Polypeptidyl-sigma-ribonucleic acid and amino-acyl-sigma-ribonucleic acid binding sites on ribosomes.
    Nature. 1966 Jul 23;211(5047):380-4 PMID: 5338626
  5. Ribosomal proteins of Escherichia coli. I. Demonstration of different primary structures.
    Proc Natl Acad Sci U S A. 1967 May;57(5):1294-301 PMID: 5341237
  6. UGA: a third nonsense triplet in the genetic code.
    Nature. 1967 Feb 4;213(5075):449-50 PMID: 6032223
  7. The release of polypeptide chains from ribosomes in cell-free amino acid-incorporating systems by specific combinations of bases in synthetic polyribonucleotides.
    Proc Natl Acad Sci U S A. 1965 Nov;54(5):1450-8 PMID: 5325655
  8. Binding of guanosine 5'-triphosphate by soluble factors required for polypeptide synthesis.
    Proc Natl Acad Sci U S A. 1968 Mar;59(3):861-8 PMID: 4868218
  9. The role of the native subribosomal particles of Escherichia coli in polypeptide chain initiation.
    Proc Natl Acad Sci U S A. 1967 Oct;58(4):1560-5 PMID: 4867664
  10. Binding of formylmethionyl-tRNA to 30S ribosomal sub-units.
    Nature. 1968 Mar 16;217(5133):1013-6 PMID: 4868440
  11. CO-LINEARITY OF THE GENE WITH THE POLYPEPTIDE CHAIN.
    Nature. 1964 Jan 4;201:13-7 PMID: 14085558
  12. Studies on polynucleotides, LXXXIV. On the role of ribosomal subunits in protein synthesis.
    Proc Natl Acad Sci U S A. 1967 Dec;58(6):2455-61 PMID: 4873591
  13. N-FORMYL-METHIONYL-S-RNA.
    J Mol Biol. 1964 Jun;8:835-40 PMID: 14187409
  14. Polypeptide chain termination using synthetic polynucleotides.
    J Mol Biol. 1965 Dec;14(2):634-9 PMID: 5326419
  15. NUCLEOTIDE SEQUENCE ANALYSIS OF POLYRIBONUCLEOTIDES BY MEANS OF PERIODATE OXIDATION FOLLOWED BY CLEAVAGE WITH AN AMINE.
    J Biol Chem. 1964 Sep;239:2927-34 PMID: 14217878
  16. Messenger RNA: an evaluation.
    Annu Rev Biochem. 1966;35:195-230 PMID: 5328353
  17. Demonstration of a guanosine triphosphate-dependent enzymatic binding of aminoacyl-ribonucleic acid to Escherichia coli ribosomes.
    Proc Natl Acad Sci U S A. 1967 Jun;57(6):1811-6 PMID: 5340636
  18. Studies on the mechanism of polypeptide chain termination in cell-free extracts of E. coli.
    Proc Natl Acad Sci U S A. 1966 Jan;55(1):162-9 PMID: 5328639
  19. PHAGE f2 RNA-DIRECTED BINDING OF FORMYLMETHIONYL-TRNA TO RIBOSOMES AND THE ROLE OF 30S RIBOSOMAL SUBUNITS IN INITIATION OF PROTEIN SYNTHESIS.
    Proc Natl Acad Sci U S A. 1967 Sep;58(3):946-53 PMID: 16578681
  20. Effect of ribosomes on the biosynthesis of ribonucleic acid in vitro.
    J Mol Biol. 1966 Nov 14;21(2):231-45 PMID: 5339604
  21. INTERACTION OF RIBOSOMES AND SYNTHETIC POLYRIBONUCLEOTIDES.
    J Mol Biol. 1963 Oct;7:323-33 PMID: 14066611
  22. AMINO ACID SUBSTITUTIONS RESULTING FROM SUPPRESSION OF NONSENSE MUTATIONS. I. SERINE INSERTION BY THE SU-1 SUPPRESSOR GENE.
    J Mol Biol. 1965 Jun;12:448-55 PMID: 14337506
  23. Genetic code: the 'nonsense' triplets for chain termination and their suppression.
    Nature. 1965 Jun 5;206(988):994-8 PMID: 5320272
  24. Studies on polynucleotides. LVI. Further syntheses, in vitro of copolypeptides containing two amino acids in alternating sequence dependent upon DNA-like polymers containing two nucleotides in alternating sequence.
    J Mol Biol. 1966 Apr;16(2):454-72 PMID: 5333513
  25. The stimulation by ribosomes of DNA transcription: requirement for a translation factor.
    Biochem Biophys Res Commun. 1967 Apr 7;27(1):12-9 PMID: 4862173
  26. THE CHROMOSOMAL SITE SPECIFYING A RIBOSOMAL PROTEIN IN ESCHERICHIA COLI.
    Proc Natl Acad Sci U S A. 1964 Dec;52:1367-74 PMID: 14243510
  27. MOLECULAR CONSEQUENCES OF THE AMBER MUTATION AND ITS SUPPRESSION.
    J Mol Biol. 1965 Jun;12:456-65 PMID: 14337507
  28. Translation of the genetic message. VII. Role of initiation factors in formation of the chain initiation complex with Escherichia coli ribosomes.
    Arch Biochem Biophys. 1968 May;125(2):542-7 PMID: 4872321
  29. Enzymatic hydrolysis of N-substituted aminoacyl-tRNA.
    Proc Natl Acad Sci U S A. 1967 Nov;58(5):2079-86 PMID: 4866985
  30. N-formylmethionyl-sRNA as the initiator of protein synthesis.
    Proc Natl Acad Sci U S A. 1966 Jan;55(1):147-55 PMID: 5328638
  31. Structure and function of E. coli ribosomes. V. Reconstitution of functionally active 30S ribosomal particles from RNA and proteins.
    Proc Natl Acad Sci U S A. 1968 Mar;59(3):777-84 PMID: 4868216
  32. Role of protein factor in the functional binding of ribosomes to natural messenger RNA.
    J Mol Biol. 1968 Apr 14;33(1):231-49 PMID: 4869226
  33. A factor from Escherichia coli concerned with the stimulation of cell-free polypeptide synthesis by exogenous ribonucleic acid. II. Characteristics of the reaction promoted by the stimulation factor.
    Biochemistry. 1966 Sep;5(9):2784-9 PMID: 5336030
  34. RNA CODEWORDS AND PROTEIN SYNTHESIS. THE EFFECT OF TRINUCLEOTIDES UPON THE BINDING OF SRNA TO RIBOSOMES.
    Science. 1964 Sep 25;145(3639):1399-407 PMID: 14172630
  35. Structure and function of E. coli ribosomes, IV. Isolation and characterization of functionally active ribosomal proteins.
    Proc Natl Acad Sci U S A. 1967 Dec;58(6):2430-6 PMID: 4873590
  36. The role of DNA in RNA synthesis, IX. Nucleoside triphosphate termini in RNA polymerase products.
    Proc Natl Acad Sci U S A. 1965 Sep;54(3):815-22 PMID: 5324397
  37. Translation of the genetic message, IV. UAA as a chain termination codon.
    Proc Natl Acad Sci U S A. 1967 Apr;57(4):1062-7 PMID: 5231346
  38. Direction of reading of the genetic message.
    J Biol Chem. 1965 Oct;240(10):3988-95 PMID: 5320647
  39. Formylmethionine codon AUG as an initiator of polypeptide synthesis.
    Science. 1966 Jul 22;153(3734):416-8 PMID: 5328567
  40. Reconstitution of functionally active ribosomes from inactive subparticles and proteins.
    Proc Natl Acad Sci U S A. 1966 Jan;55(1):198-204 PMID: 5328641
  41. GTP interaction with a protein synthesis initiation factor preparation from Escherichia coli.
    Biochem Biophys Res Commun. 1967 Jul 10;28(1):82-8 PMID: 4860633
  42. Ribosomal proteins of Escherichia coli. II. Proteins from the 30 s subunit.
    J Mol Biol. 1968 Feb 14;31(3):441-61 PMID: 4866333
  43. Polypeptide synthesis in Escherichia coli. II. The polypeptide chain and S-RNA.
    J Mol Biol. 1963 May;6:389-403 PMID: 13947831
  44. Translocation in protein synthesis: a hybrid structure model.
    Nature. 1968 May 18;218(5142):675-7 PMID: 5655957
  45. Biological activity of the re-assembled ribosome-like particles.
    J Mol Biol. 1966 Jan;15(1):282-3 PMID: 5330220
  46. Direction of synthesis of messenger RNA in cells of Escherichia coli.
    Proc Natl Acad Sci U S A. 1965 Dec;54(6):1669-75 PMID: 5326384
  47. A strong suppressor specific for UGA.
    Nature. 1967 Apr 29;214(5087):452-3 PMID: 5340340
  48. Polypeptide chain termination in vitro: isolation of a release factor.
    Proc Natl Acad Sci U S A. 1967 Sep;58(3):1144-51 PMID: 5233840
  49. Amber suppression: a nucleotide change in the anticodon of a tyrosine transfer RNA.
    Nature. 1968 Mar 16;217(5133):1019-24 PMID: 5643523
  50. In vitro recovery o ribosomes and of synthetic activity from synthetically inactive ribosomal subunits.
    J Mol Biol. 1966 Mar;16(1):245-9 PMID: 5331242
  51. Protein synthesis.
    Annu Rev Biochem. 1966;35:723-58 PMID: 5329473
  52. Initiation of polyphenylalanine synthesis by N-acetylphenylalanyl-SRNA.
    Proc Natl Acad Sci U S A. 1967 Apr;57(4):1050-7 PMID: 5340585
  53. Initiation of protein synthesis. 3. Factor-GTP-codon-dependent binding of F-met-tRNA to ribosomes.
    Proc Natl Acad Sci U S A. 1967 Aug;58(2):774-81 PMID: 4860758
  54. Formylmethionyl-tRNA dependence of amino acid incorporation in extracts of trimethoprim-treated Escherichia coli.
    Science. 1966 Oct 28;154(3748):524-7 PMID: 5331096
  55. A GTP requirement for binding initiator tRNA to ribosomes.
    Nature. 1967 Jul 29;215(5100):490-2 PMID: 4862225
  56. Protein factor requirement for binding of messenger RNA to ribosomes.
    Biochem Biophys Res Commun. 1968 Feb 15;30(3):284-91 PMID: 4869543
  57. Change of a sequence of amino acids in phage T4 lysozyme by acridine-induced mutations.
    Proc Natl Acad Sci U S A. 1966 Aug;56(2):500-7 PMID: 5229972
  58. Comparison of guanosine triphosphate split and polypeptide synthesis with a purified E. coli system.
    Proc Natl Acad Sci U S A. 1966 Jan;55(1):212-9 PMID: 4287350
  59. RNA codewords and protein synthesis, VII. On the general nature of the RNA code.
    Proc Natl Acad Sci U S A. 1965 May;53(5):1161-8 PMID: 5330357
  60. Studies on polynucleotides. LXVII. Initiation of protein synthesis in vitro as studied by using ribopolynucleotides with repeating nucleotide sequences as messengers.
    J Mol Biol. 1967 Apr 28;25(2):275-98 PMID: 5340533
  61. Translation of the genetic message, ii. Effect of initiation factors on the binding of formyl-methionyl-trna to ribosomes.
    Proc Natl Acad Sci U S A. 1967 Feb;57(2):387-94 PMID: 16591482
  62. Initiation of protein synthesis II. A convenient assay for the ribosome-dependent synthesis of N-formyl-C14-methionylpuromycin.
    Biochem Biophys Res Commun. 1966 Oct 20;25(2):233-8 PMID: 5339543
  63. The formation and stabilization of 30S and 50S ribosome couples in Escherichia coli.
    Proc Natl Acad Sci U S A. 1967 Oct;58(4):1782-9 PMID: 4867673
  64. N-formyl-methionyl-sigma-ribonucleic acid and chain initiation in protein biosynthesis. Polypeptide synthesis directed by a bacteriophage ribonucleic acid in a cell-free system.
    Nature. 1966 Jul 23;211(5047):378-80 PMID: 5967823
  65. A factor from E. coli required for the translation of natural messenger RNA.
    Biochem Biophys Res Commun. 1966 Oct 5;25(1):124-32 PMID: 5339540
  66. Base composition of nonsense codons in E. coli. Evidence from amino-acid substitutions at a tryptophan site in alkaline phosphatase.
    Nature. 1965 Jun 5;206(988):992-4 PMID: 5320271
  67. Catalysis of peptide bond formation by 50 S ribosomal subunits from Escherichia coli.
    J Mol Biol. 1967 May 28;26(1):147-51 PMID: 5341411
  68. A stepwise reaction yielding a complex between a supernatant fraction from E. coli, guanosine 5'-triphosphate, and aminoacyl-sRNA.
    Proc Natl Acad Sci U S A. 1968 Jan;59(1):179-83 PMID: 4873342
  69. Studies on the translation of the genetic message. II. Translation of oligonucleotide messengers of specified base sequence.
    Cold Spring Harb Symp Quant Biol. 1966;31:103-11 PMID: 4866368
  70. Translation of the genetic message. V. Effect of Mg++ and formylation of methionine in protein synthesis.
    Proc Natl Acad Sci U S A. 1967 Jun;57(6):1865-9 PMID: 5340638
  71. In vitro protein synthesis: chain initiation.
    Proc Natl Acad Sci U S A. 1966 Jan;55(1):155-61 PMID: 5220863
  72. The initiation of protein synthesis: joining of the 50S ribosomal subunit to the initiation complex.
    Proc Natl Acad Sci U S A. 1967 Oct;58(4):1487-93 PMID: 4867661
  73. The role of N-formyl-methionyl-sRNA in protein biosynthesis.
    J Mol Biol. 1966 Jun;17(2):394-406 PMID: 5336478
  74. MECHANISM OF PEPTIDE BOND FORMATION IN POLYPEPTIDE SYNTHESIS.
    Proc Natl Acad Sci U S A. 1964 Jun;51:1291-9 PMID: 14215654
  75. Initiation of E. coli proteins.
    Proc Natl Acad Sci U S A. 1966 Jun;55(6):1517-24 PMID: 5336288
  76. Direction of chain growth in enzymic RNA synthesis.
    J Mol Biol. 1965 Sep;13(2):540-53 PMID: 5867035
  77. Translation of the genetic message. VI. The role of ribosomal subunits in binding of formylmethionyl-tRNA and its reaction with puromycin.
    Proc Natl Acad Sci U S A. 1967 Oct;58(4):1652-4 PMID: 4867669
  78. THE OPERON: ON ITS THIRD ANNIVERSARY. MODULATION OF TRANSFER RNA SPECIES CAN PROVIDE A WORKABLE MODEL OF AN OPERATOR-LESS OPERON.
    Science. 1964 May 15;144(3620):816-20 PMID: 14149392
  79. Translation of the genetic message: factors involved in the initiation of protein synthesis.
    Proc Natl Acad Sci U S A. 1966 Jul;56(1):290-5 PMID: 5338590
Article Info
Journal
Die Naturwissenschaften
Abbr.
Naturwissenschaften
ISSN
0028-1042
DOI
10.1007/BF00660121
Published
1968-11-00
Pages
505-14
Language
English
Region
Germany
NLM ID
0400767
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00660121 View journal details
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