The specific radioactivity of the precursor pool for estimates of the rate of protein synthesis.

The Biochemical journal ·Vol. 134 ·No. 4 ·1973-08-00 ·Pages 1127-30

Fern EB, Garlick PJ

Abstract

Infusion of rats with [U-(14)C]glycine resulted in labelling of glycine and serine in tissue proteins. The pattern of labelling in protein more nearly resembled that of the free amino acids in the tissue than in the plasma.

MeSH Terms

Animals Carbon Radioisotopes Diaphragm/metabolism Female Glycine/metabolism Hydrolysis Liver/metabolism Muscles/metabolism Myocardium/metabolism Protein Biosynthesis Rats Serine/metabolism

Chemicals

Carbon Radioisotopes Serine Glycine

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Fern E B

Garlick P J

References (12)

12 references, click to expand

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Turnover rate of muscle protein measured by constant intravenous infusion of 14C-glycine.
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Regulation of protein synthesis in heart muscle. I. Effect of amino acid levels on protein synthesis.
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Identification in skeletal muscle of a distinct extracellular pool of amino acids, and its role in protein synthesis.
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A technique for measuring brain protein synthesis.
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Evidence for the selection by the membrane transport system of intracellular or extracellular amino acids for protein synthesis.
Biochim Biophys Acta. 1972 Sep 1;282(1):352-65 PMID: 5070083
The rate of incorporation of amino acids into brain proteins during infusion in the rat.
Biochim Biophys Acta. 1973 Feb 4;294(1):472-80 PMID: 4705996
Quantitative aspects of glycine metabolism in the rabbit.
Biochem J. 1955 Jul;60(3):409-24 PMID: 13239574
Functional heterogeneity of the intracellular amino acid pool in mammalian cells.
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Article Info

Journal

The Biochemical journal

Abbr.

Biochem J

ISSN

0264-6021

DOI

10.1042/bj1341127

Published

1973-08-00

Pages

1127-30

Language

English

Region

England

NLM ID

2984726R

PMCID

PMC1177923

Subset

External Links

PubMed source DOI: 10.1042/bj1341127 PMC Full Text View journal details

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The specific radioactivity of the precursor pool for estimates of the rate of protein synthesis.

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