Home LiteratureArticle Details
PMID: 4689832 Published · ppublish English Clinical Trial Journal Article Randomized Controlled Trial

Effect of metoclopramide on gastric emptying during labour.

British medical journal ·Vol. 1 ·No. 5851 ·1973-02-24 ·Pages 446-8

Howard FA, Sharp DS

Abstract

The effect of a single dose of metoclopramide (Maxolon) on the gastric emptying rate of a liquid test meal was measured in a group of parturient women by a double-sampling dye-dilution technique. The subjects were given either metoclopramide 10 mg or sterile water by intramuscular injection on a double-blind random basis at the start of the test. The gastric emptying rate was significantly increased in those women who had received the metoclopramide as compared with those who had received the placebo.

MeSH Terms
Amides/pharmacology Anesthesia, Obstetrical/adverse effects Anisoles/pharmacology Benzoates/pharmacology Ethylamines/pharmacology Female Fetus/drug effects Gastrointestinal Motility/drug effects Half-Life Humans Intubation, Gastrointestinal Labor, Induced Labor, Obstetric Pregnancy Pregnancy Complications/etiology Stomach/drug effects Time Factors Vomiting
Chemicals
Amides Anisoles Benzoates Ethylamines
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Howard F A
Sharp D S
References (9)
9 references, click to expand
  1. The saline load test--a bedside evaluation of gastric retention.
    Gastroenterology. 1965 Oct;49(4):375-80 PMID: 5831782
  2. Gastrointestinal actions of metoclopramide. An experimental study.
    Gastroenterology. 1967 Apr;52(4):676-84 PMID: 4960492
  3. New clinical method for measuring the rate of gastric emptying: the double sampling test meal.
    Gut. 1968 Apr;9(2):237-42 PMID: 4871724
  4. Gastrointestinal effects of metoclopramide in man. In vitro experiments with human smooth muscle preparations.
    Br Med J. 1968 Dec 14;4(5632):679-80 PMID: 5723387
  5. Gastric emptying time in late pregnancy and labour.
    J Obstet Gynaecol Br Commonw. 1970 Jan;77(1):37-41 PMID: 5419869
  6. Controlled trial of metoclopramide in the treatment of flatulent dyspepsia.
    Br Med J. 1971 Apr 3;2(5752):25-6 PMID: 4927813
  7. [METOCLOPRAMIDE AND ITS HOMOLOGUES. INTRODUCTION TO THEIR BIOLOGICAL STUDY].
    C R Hebd Seances Acad Sci. 1964 Apr 27;258:4384-6 PMID: 14146821
  8. [METOCLOPRAMIDE AND THE APOMORPHINE TEST IN THE RAT].
    Pathol Biol (Paris). 1964 Jun-Jul;12:726-7 PMID: 14187722
  9. The prevention of inhaled vomit during obstetric anesthesia.
    J Obstet Gynaecol Br Emp. 1956 Apr;63(2):239-40 PMID: 13320221
Article Info
Journal
British medical journal
Abbr.
Br Med J
ISSN
0007-1447
Published
1973-02-24
Pages
446-8
Language
English
Region
England
NLM ID
0372673
PMCID
PMC1588429
Subset
IM
External Links
PubMed source PMC Full Text
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2