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PMID: 4589860 Published · ppublish English Journal Article

Unfolding of the host genome after infection of Escherichia coli with bacteriophage T4.

Journal of virology ·Vol. 13 ·No. 2 ·1974-02-00 ·Pages 548-50

Tutas DJ, Wehner JM, Koerner JF

Abstract

The folded genome of Escherichia coli is converted to a slower-sedimenting form within 5 min after infection with bacteriophage T4 or T4nd28(den A)-amN82(44). Chloramphenicol sensitivity and response to UV-irradiation of the phage suggest participation of viral-induced functions.

MeSH Terms
Carbon Radioisotopes Centrifugation, Density Gradient Chloramphenicol/pharmacology Coliphages/growth & development,radiation effects DNA, Bacterial/analysis,metabolism Escherichia coli/analysis,metabolism Nucleic Acid Denaturation Radiation Effects Thymidine Tritium Ultraviolet Rays Viscosity
Chemicals
Carbon Radioisotopes DNA, Bacterial Tritium Chloramphenicol Thymidine
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Tutas D J
Wehner J M
Koerner J F
References (11)
11 references, click to expand
  1. EFFECT OF ULTRAVIOLET IRRADIATION OF BACTERIOPHAGE T2 ON ENZYME SYNTHESIS IN HOST CELLS.
    Proc Natl Acad Sci U S A. 1960 Nov;46(11):1425-30 PMID: 16590767
  2. Enzymatic breakage of deoxyribonucleic acid. II. Purification and properties of endonuclease IV from T4 phage-infected Escherichia coli.
    J Biol Chem. 1969 Nov 25;244(22):6192-8 PMID: 4900512
  3. Degradation of cytosin-containing bacterial and bacteriophage DNA after infection of Escherichia coli B with bacteriophage T4D wild type and with mutants defective in genes 46, 47 and 56.
    J Mol Biol. 1968 Dec;38(3):395-411 PMID: 4305016
  4. The folded genome of Escherichia coli isolated in a protein-DNA-RNA complex.
    Proc Natl Acad Sci U S A. 1971 Jan;68(1):6-9 PMID: 4924971
  5. Nuclear disruption after infection of Escherichia coli with a bacteriophage T4 mutant unable to induce endonuclease II.
    J Virol. 1972 Jul;10(1):124-33 PMID: 4114321
  6. THE SYNTHESIS OF MESSENGER RNA WITHOUT PROTEIN SYNTHESIS. II. SYNTHESIS OF PHAGE-INDUCED RNA AND SEQUENTIAL ENZYME PRODUCTION.
    J Mol Biol. 1964 May;8:638-59 PMID: 14187391
  7. Mutants of bacteriophage T4 defective in the induction of T4 endonuclease II.
    J Biol Chem. 1971 May 25;246(10):3431-3 PMID: 4930062
  8. Isolation of bacteriophage T4 mutants defective in the ability to degrade host deoxyribonucleic acid.
    J Virol. 1970 Jun;5(6):700-8 PMID: 4914096
  9. The ability of irradiated bacteriophage T2 to initiate the synthesis of deoxycytidylate hydroxymethylase in Escherichia coli.
    Virology. 1961 Feb;13:242-8 PMID: 13721573
  10. Mutants in a nonessential gene of bacteriophage T4 which are defective in the degradation of Escherichia coli deoxyribonucleic acid.
    J Virol. 1971 Jan;7(1):95-105 PMID: 5543437
  11. On the structure of the folded chromosome of Escherichia coli.
    J Mol Biol. 1972 Nov 14;71(2):127-47 PMID: 4564477
Article Info
Journal
Journal of virology
Abbr.
J Virol
ISSN
0022-538X
DOI
10.1128/JVI.13.2.548-550.1974
Published
1974-02-00
Pages
548-50
Language
English
Region
United States
NLM ID
0113724
PMCID
PMC355330
Subset
IM
External Links
PubMed source DOI: 10.1128/JVI.13.2.548-550.1974 PMC Full Text View journal details
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