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PMID: 4574707 Published · ppublish English Journal Article

Transcriptional control of the calactose operon by the capR (lon) and capT genes.

Journal of bacteriology ·Vol. 114 ·No. 2 ·1973-05-00 ·Pages 891-3

Buchanan CE, Hua SS, Avni H, Markovitz A

Abstract

Mutations in capR or capT cause derepression of the enzymes of the gal operon. The gal-specific messenger ribonucleic acid is directly proportional to the gal enzyme levels in wild type, capR, and capT strains. These results indicate that capR and capT control the gal operon at the transcriptional level.

MeSH Terms
Cell-Free System DNA, Bacterial Escherichia coli/enzymology,metabolism Galactose/metabolism Genes Isomerases/metabolism Mutation Nucleic Acid Hybridization Operon Phosphotransferases/metabolism RNA, Bacterial/biosynthesis RNA, Messenger/biosynthesis Transcription, Genetic Tritium
Chemicals
DNA, Bacterial RNA, Bacterial RNA, Messenger Tritium Phosphotransferases Isomerases Galactose
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Buchanan C E
Hua S S
Avni H
Markovitz A
References (14)
14 references, click to expand
  1. Synthesis and turnover of phage messenger RNA in E. coli infected with bacteriophage T4 in the presence of chloromycetin.
    J Mol Biol. 1962 Nov;5:527-34 PMID: 13939775
  2. Multiple regulator gene control of the galactose operon in Escherichia coli K-12.
    J Bacteriol. 1972 Jun;110(3):1089-99 PMID: 4555404
  3. The galactose operon of E. coli K-12. II. A deletion analysis of operon structure and polarity.
    Genetics. 1969 Jun;62(2):249-64 PMID: 4905872
  4. Isolation of the gal repressor.
    Proc Natl Acad Sci U S A. 1971 Aug;68(8):1891-5 PMID: 4942917
  5. [REGULATORY MECHANISMS IN THE BIOSYNTHESIS OF THE ENZYMES OF GALACTOSE METABOLISM IN ESCHERICHIA COLI K 12. II. THE GENETIC DETERMINISM OF THE REGULATION].
    J Mol Biol. 1963 Aug;7:183-205 PMID: 14062651
  6. HEREDITARY DEFECTS IN GALACTOSE METABOLISM IN ESCHERICHIA COLI MUTANTS, I. DETERMINATION OF ENZYME ACTIVITIES.
    Proc Natl Acad Sci U S A. 1959 Dec;45(12):1776-86 PMID: 16590575
  7. Regulation of lac messenger ribonucleic acid synthesis by cyclic adenosine 3',5'-monophosphate and glucose.
    J Biol Chem. 1970 May 10;245(9):2259-67 PMID: 4315149
  8. Regulation of gal messenger ribonucleic acid synthesis in Escherichia coli by 3',5'-cyclic adenosine monophosphate.
    J Biol Chem. 1971 May 10;246(9):2898-903 PMID: 4324343
  9. A quantitative assay for DNA-RNA hybrids with DNA immobilized on a membrane.
    J Mol Biol. 1965 Jul;12(3):829-42 PMID: 4955314
  10. Isolation of plaque-forming, galactose-transducing strains of phage lambda.
    Genetics. 1972 Jun;71(2):189-206 PMID: 4558323
  11. Orientation of transcription for the galactose operon as determined by hybridization of gal mRNA with the separated DNA strands of coliphages lambda-dg.
    J Mol Biol. 1968 Jul 14;35(1):207-13 PMID: 4939778
  12. Protein measurement with the Folin phenol reagent.
    J Biol Chem. 1951 Nov;193(1):265-75 PMID: 14907713
  13. Negative control of the galactose operon in E. coli.
    Mol Gen Genet. 1968;102(1):79-88 PMID: 4883532
  14. Regulation of the gal operon of Escherichia coli by the capR gene.
    J Biol Chem. 1972 May 25;247(10):2973-8 PMID: 4337501
Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
Published
1973-05-00
Pages
891-3
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC251856
Subset
IM
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