Serological crossreactivity between H-Y (male) antigens of mouse and man.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 71 ·No. 4 ·1974-04-00 ·Pages 1215-8

Wachtel SS, Koo GC, Zuckerman EE, Hammerling U, Scheid MP, Boyse EA

Abstract

Antisera to H-Y (male-specific) antigen were prepared by immunizing female mice with spleen cells from males of the same inbred strain. These antisera were used in mixed hemadsorption and cytotoxicity tests with cells of rats, guinea pigs, rabbits, and humans. The results showed that the H-Y components of all four species are antigenically related to H-Y of the mouse.

MeSH Terms

Animals Antibodies, Heterophile Antigens, Heterophile Cross Reactions Cytotoxicity Tests, Immunologic Erythrocytes/immunology Guinea Pigs Histocompatibility Antigens/analysis Humans Immune Adherence Reaction Immune Sera Male Mice Mice, Inbred BALB C Rats Rats, Inbred WF Sex Chromosomes/immunology Sheep/immunology Species Specificity Spermatozoa/immunology

Chemicals

Antibodies, Heterophile Antigens, Heterophile Histocompatibility Antigens Immune Sera

Authors & Affiliations

6 authors, click to expand affiliations / ORCID

Wachtel S S

Koo G C

Zuckerman E E

Hammerling U

Scheid M P

Boyse E A

References (10)

10 references, click to expand

Skin.
Transplant Bull. 1955;2:148-9 PMID: 12334405
Serological demonstration of H-Y (male) antigen on mouse sperm.
Nature. 1971 Aug 13;232(5311):478-80 PMID: 4937209
Immunogenetic components of weaker histoincompatibility systems in mice.
Transplant Proc. 1970 Mar;2(1):24-31 PMID: 4940353
Serologically demonstrable alloantigens of mouse epidermal cells.
J Exp Med. 1972 Apr 1;135(4):938-55 PMID: 4553016
X- and Y-linked transplantation antigens in rats.
Transplantation. 1972 May;13(5):521-9 PMID: 4557800
Serological detection of a cell-surface antigen specified by the T (brachyury) mutant gene in the house mouse.
Proc Natl Acad Sci U S A. 1972 Aug;69(8):2076-80 PMID: 4506076
H-2 antigens on mouse spermatozoa.
Transplantation. 1972 Dec;14(6):781-6 PMID: 4566272
Rosette formation by human thymocytes.
Cell Immunol. 1973 Mar;6(3):362-7 PMID: 4632364
Topographical location of H-Y antigen on mouse spermatozoa by immunoelectronmicroscopy.
Proc Natl Acad Sci U S A. 1973 May;70(5):1502-5 PMID: 4576022
Male specific antigen: homology in mice and rats.
Science. 1973 Aug 10;181(4099):570-2 PMID: 4578607

Article Info

Journal

Proceedings of the National Academy of Sciences of the United States of America

Abbr.

Proc Natl Acad Sci U S A

ISSN

0027-8424

DOI

10.1073/pnas.71.4.1215

Published

1974-04-00

Pages

1215-8

Language

English

Region

United States

NLM ID

7505876

PMCID

PMC388195

Subset

External Links

PubMed source DOI: 10.1073/pnas.71.4.1215 PMC Full Text View journal details

Analysis Services

Serological crossreactivity between H-Y (male) antigens of mouse and man.

Contact

WeChat Official Account