Preliminary observations pertaining to polyadenylation of rhinovirus RNA.

Journal of virology ·Vol. 13 ·No. 2 ·1974-02-00 ·Pages 535-7

Nair CN, Owens MJ

Abstract

Human rhinovirus type 14 contained polyadenylated RNA. Virus growth in HeLa cells was inhibited by cordycepin or polyuridilic acid and stimulated by polyadenylic acid. Polyadenylic acid also reversed cordycepin inhibition of virus-induced cytopathology of infected HeLa cells.

MeSH Terms

Adenine Nucleotides/analysis,pharmacology Adenosine Ascomycota Cytopathogenic Effect, Viral/drug effects Fungal Proteins/pharmacology HeLa Cells Humans Micropore Filters Poly U/pharmacology Polynucleotides/analysis,pharmacology RNA, Viral/analysis Rhinovirus/analysis,growth & development Ribonucleases Tritium Viral Plaque Assay Virus Replication/drug effects

Chemicals

Adenine Nucleotides Fungal Proteins Polynucleotides RNA, Viral Tritium Poly U Ribonucleases Adenosine

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Nair C N

Owens M J

References (16)

16 references, click to expand

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Article Info

Journal

Journal of virology

Abbr.

J Virol

ISSN

0022-538X

DOI

10.1128/JVI.13.2.535-537.1974

Published

1974-02-00

Pages

535-7

Language

English

Region

United States

NLM ID

0113724

PMCID

PMC355326

Subset

External Links

PubMed source DOI: 10.1128/JVI.13.2.535-537.1974 PMC Full Text View journal details

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Preliminary observations pertaining to polyadenylation of rhinovirus RNA.

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