Virus-induced proteins in pseudorabies-infected cells. I. Acid-extractable proteins of the nucleus.

Journal of virology ·Vol. 11 ·No. 6 ·1973-06-00 ·Pages 815-22

Chantler JK, Stevely WS

Abstract

Three basic proteins have been identified in chromatin preparations from pseudorabies virus-infected cells. They appear to be virus specified and are similar in size and charge to host histones; one difference however is that they contain tryptophan. All are produced by 3 h postinfection, and two (IP II and III) seem to be arginine rich. Three similar proteins are also found in herpes simplex MP 17-infected cells, and two of these co-electrophorese with two of the pseudorabies proteins. Partially purified preparations of pseudorabies virus contain low amounts of all three proteins.

MeSH Terms

Animals Arginine/metabolism Carbon Isotopes Cell Line Cell Nucleus/analysis,metabolism Cells, Cultured/metabolism,microbiology Centrifugation, Density Gradient Chromatin/analysis Cricetinae Electrophoresis, Polyacrylamide Gel Herpesviridae/analysis,growth & development,metabolism Kidney Methionine/metabolism Pseudorabies/microbiology Simplexvirus/analysis Time Factors Tritium Tryptophan/metabolism Viral Proteins/analysis,biosynthesis,isolation & purification

Chemicals

Carbon Isotopes Chromatin Viral Proteins Tritium Tryptophan Arginine Methionine

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Chantler J K

Stevely W S

References (12)

12 references, click to expand

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A comparison of herpes simplex and pseudorabies viruses.
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Article Info

Journal

Journal of virology

Abbr.

J Virol

ISSN

0022-538X

DOI

10.1128/JVI.11.6.815-822.1973

Published

1973-06-00

Pages

815-22

Language

English

Region

United States

NLM ID

0113724

PMCID

PMC355187

Subset

External Links

PubMed source DOI: 10.1128/JVI.11.6.815-822.1973 PMC Full Text View journal details

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Virus-induced proteins in pseudorabies-infected cells. I. Acid-extractable proteins of the nucleus.

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