AMINO ACID REQUIREMENTS OF HERPES SIMPLEX VIRUS IN HUMAN CELLS.

Journal of bacteriology ·Vol. 87 ·1964-03-00 ·Pages 609-13

TANKERSLEY RW

Abstract

Tankersley, Robert W., Jr. (Medical College of Virginia, Richmond). Amino acid requirements of herpes simplex virus in human cells. J. Bacteriol. 87:609-613. 1964.-Progressive infection of human cells minimally infected with herpes simplex virus requires 11 of the amino acids of Eagle's medium, and glutamine. Lysine is not required, but rather exerts a partially inhibitory effect upon virus multiplication. Infected cells deprived of arginine support neither cytopathogenic effects nor virus replication; when arginine is replaced, a prompt and extensive infection follows. The effect of nutritional deficiencies on virus infection is discussed.

Keywords

AMINO ACIDS ARGININE CULTURE MEDIA EXPERIMENTAL LAB STUDY HERPESVIRUS HOMINIS HERPESVIRUS INFECTIONS

MeSH Terms

Amino Acids Arginine Culture Media Glutamine Herpesviridae Infections Humans Lysine Research Simplexvirus Virus Replication

Chemicals

Amino Acids Culture Media Glutamine Arginine Lysine

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

TANKERSLEY R W

References (13)

13 references, click to expand

Mammalian cell cultures contaminated with pleuropneumonia-like organisms. I. Effect of pleuropneumonia-like organisms on growth of established cell strains.
J Infect Dis. 1963 Jan-Feb;112:7-16 PMID: 14031982
Effects of certain amino acids and related compounds on propagation of mouse encephalomyelitis virus.
Proc Soc Exp Biol Med. 1952 Mar;79(3):409-11 PMID: 14920444
Human cells in continuous culture. I. Derivation of cell strains from esophagus, palate, liver, and lung.
Cancer Res. 1957 Oct;17(9):923-6 PMID: 13472685
Nutrition needs of mammalian cells in tissue culture.
Science. 1955 Sep 16;122(3168):501-14 PMID: 13255879
Factors influencing the proliferation of viruses.
Tex Rep Biol Med. 1957;15(3):496-532; discussion 532-3 PMID: 13495954
The nutritional requirements for the propagation of poliomyelitis virus by the HeLa cell.
J Exp Med. 1956 Aug 1;104(2):271-87 PMID: 13345971
Nutritional requirements for the production of herpes simplex virus. I. Influence of glucose and glutamine of herpes simplex virus production by HeLa cells.
J Bacteriol. 1962 Mar;83:475-82 PMID: 14464909
Latent viral infection of cells in tissue culture. VII. Role of water-soluble vitamins in psittacosis virus propagation in L cells.
J Exp Med. 1961 Feb 1;113:271-81 PMID: 13685754
Defined medium for growth of foot-and-mouth disease virus.
J Bacteriol. 1962 Mar;83:579-83 PMID: 14487167
Latent viral infection of cells in tissue culture. VI. Role of amino acids, glutamine, and glucose in psittacosis virus propagation in L cells.
J Exp Med. 1958 Nov 1;108(5):617-30 PMID: 13587846
Latent viral infection of cells in tissue culture. IV. Latent infection of L cells with psittacosis virus.
J Exp Med. 1957 Jul 1;106(1):39-44 PMID: 13439113
Use of arginine to eliminate medium changes in tissue culture systems.
Science. 1958 Mar 14;127(3298):591-2 PMID: 13529024
The formation of microscopic plaques by herpes simplex virus in HeLa cells.
Virology. 1958 Oct;6(2):317-27 PMID: 13593174

Article Info

Journal

Journal of bacteriology

Abbr.

J Bacteriol

ISSN

0021-9193

DOI

10.1128/jb.87.3.609-613.1964

Published

1964-03-00

Pages

609-13

Language

English

Region

United States

NLM ID

2985120R

PMCID

PMC277062

Subset

External Links

PubMed source DOI: 10.1128/jb.87.3.609-613.1964 PMC Full Text View journal details

Analysis Services

AMINO ACID REQUIREMENTS OF HERPES SIMPLEX VIRUS IN HUMAN CELLS.

Contact

WeChat Official Account