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PMID: 4346890 Published · ppublish English Journal Article

Adenosine 3':5'-cyclic monophosphate as a regulator of bacterial transformation.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 70 ·No. 2 ·1973-02-00 ·Pages 471-4

Wise EM, Alexander SP, Powers M

Abstract

Adenosine 3':5'-cyclic monophosphate added to exponentially growing cells of Hemophilus influenzae strain Rd increases competence for transformation 100- to 10,000-fold. Cyclic AMP added to near-stationary or stationary cells does not increase competence over the high level normally found in the early stationary phase.

MeSH Terms
Cyclic AMP/pharmacology Drug Resistance, Microbial Haemophilus influenzae/drug effects,growth & development Novobiocin/pharmacology Spectrum Analysis Streptomycin/pharmacology Time Factors Transformation, Genetic/drug effects
Chemicals
Novobiocin Cyclic AMP Streptomycin
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Wise E M
Alexander S P
Powers M
References (25)
25 references, click to expand
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Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
DOI
10.1073/pnas.70.2.471
Published
1973-02-00
Pages
471-4
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC433285
Subset
IM
External Links
PubMed source DOI: 10.1073/pnas.70.2.471 PMC Full Text View journal details
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