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PMID: 424292 Published · ppublish English Journal Article

Multiacetylated forms of H4 are found in a putative transcriptionally competent chromatin fraction from trout testis.

Nucleic acids research ·Vol. 6 ·No. 1 ·1979-01-00 ·Pages 259-74

Levy-Wilson B, Watson DC, Dixon GH

Abstract

We have examined the distribution of acetylated histones derived from various trout testis chromatin fractions of different composition. Our results indicate that a chromatin fraction, preferentially solubilized by micrococcal nuclease, containing the bulk of the HMG proteins and similar to a fraction released from intact trout nuclei and previously shown to be enriched in transcribed DNA sequences also possesses high levels of multiacetylated species of H4. Histones 2A, 2B and 3 are also acetylated in this particular chromatin fraction. Monoacetylated species of the 4 inner nucleosomal histones appear to be characteristic of the nucleohistone portion of trout testis chromatin.

MeSH Terms
Acetates/metabolism Acetylation Animals Chromatin/metabolism Histones/isolation & purification,metabolism Male Molecular Weight Testis/metabolism Transcription, Genetic Trout
Chemicals
Acetates Chromatin Histones
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Levy-Wilson B
Watson D C
Dixon G H
References (22)
22 references, click to expand
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Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
0305-1048
DOI
10.1093/nar/6.1.259
Published
1979-01-00
Pages
259-74
Language
English
Region
England
NLM ID
0411011
PMCID
PMC327687
Subset
IM
External Links
PubMed source DOI: 10.1093/nar/6.1.259 PMC Full Text View journal details
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