Home LiteratureArticle Details
PMID: 4165816 Published · ppublish English Journal Article

Insulin regulation of protein synthesis by muscle ribosomes: effect of the hormone on translation of messenger RNA for a regulatory protein.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 56 ·No. 3 ·1966-09-00 ·Pages 991-8

Wool IG, Cavicchi P

Abstract

暂无摘要

MeSH Terms
Animals Cycloheximide/pharmacology Dactinomycin/pharmacology Diabetes Mellitus, Experimental/metabolism Genetic Code In Vitro Techniques Insulin/pharmacology Muscle Proteins/biosynthesis Muscles/cytology,metabolism Myocardium/metabolism Phenylalanine/metabolism Puromycin/pharmacology RNA, Messenger/metabolism Rats Ribosomes/drug effects,metabolism
Chemicals
Insulin Muscle Proteins RNA, Messenger Dactinomycin Phenylalanine Puromycin Cycloheximide
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Wool I G
Cavicchi P
References (20)
20 references, click to expand
  1. Experiments on hemoglobin biosynthesis.
    Proc Natl Acad Sci U S A. 1961 Jul 15;47:941-50 PMID: 13782056
  2. Effect of insulin on the incorporation of C14 from C14-labeled carboxylic acids and bicarbonate into the protein of isolated rat diaphragm.
    J Biol Chem. 1959 Nov;234:2938-42 PMID: 14420490
  3. An effect of insulin on peptide synthesis independent of glucose or amino-acid transport.
    Nature. 1959 May 16;183(4672):1399-400 PMID: 13657137
  4. Effect of insulin on distribution of radioactivity in protein of cell fractions from isolated rat diaphragm.
    Biochim Biophys Acta. 1961 Sep 30;52:574-6 PMID: 14008267
  5. Protein synthesis by ribosomes from heart muscle: effect of insulin and diabetes.
    Science. 1965 Sep 3;149(3688):1102-3 PMID: 5826524
  6. Incorporation of C14-amino acids into protein of isolated diaphragms: an effect of insulin independent of glucose entry.
    Am J Physiol. 1959 May;196(5):961-4 PMID: 13649907
  7. The effect of insulin on incorporation of amino acids into protein of normal rat diaphragm in vitro.
    Biochem J. 1958 Nov;70(3):353-8 PMID: 13596350
  8. Loss of ribonucleic acid into lipid solvents after acid precipitation.
    Biochim Biophys Acta. 1963 Jan 29;68:131-3 PMID: 13952187
  9. Relation of effects of insulin on amino acid transport and on protein synthesis.
    Fed Proc. 1965 Sep-Oct;24(5):1060-70 PMID: 5838176
  10. Isolation and characterization of ribonucleoprotein particles from heart muscle.
    Biochim Biophys Acta. 1965 Sep 6;108(1):95-105 PMID: 5862246
  11. Amino acid incorporation into protein by cell-free systems from rat skeletal muscle. V. Effects of pituitary growth hormone on activity of ribosomes and ribonucleic acid polymerase in hypophysectomized rats.
    Biochemistry. 1966 Jun;5(6):1870-6 PMID: 5963429
  12. The effect of insulin on the incorporation of C14 into the protein of rat diaphragm.
    J Biol Chem. 1952 Oct;198(2):615-9 PMID: 12999777
  13. The precision of ultraviolet absorption measurements in the Schmidt-Thannhauser procedure for nucleic acid estimation.
    Biochim Biophys Acta. 1962 May 14;55:571-83 PMID: 13893456
  14. EFFECT OF ACTINOMYCIN AND INSULIN ON THE METABOLISM OF ISOLATED RAT DIAPHRAGM.
    Biochim Biophys Acta. 1964 Oct 16;91:248-56 PMID: 14240642
  15. EFFECT OF INSULIN IN VITRO ON INCORPORATION OF 14-D FROM PYRUVATE INTO THE PROTEIN OF ISOLATED RAT DIAPHRAGM IN THE PRESENCE OF (12-CALANINE,(12-C)ASPARTIC ACID AND(12-C)GLUTAMIC ACID.
    Biochim Biophys Acta. 1964 Mar 16;82:606-8 PMID: 14148827
  16. Studies on the role of protein synthesis in the regulation of corticosterone production by adrenocorticotropic hormone in vivo.
    Proc Natl Acad Sci U S A. 1965 Jun;53(6):1443-50 PMID: 4285998
  17. Effect of insulin and diabetes on protein synthesis by ribosomes from heart muscle. Significance for theories of the hormone's mechanism of action.
    Am J Med. 1966 May;40(5):716-23 PMID: 5941967
  18. MECHANISM OF PEPTIDE BOND FORMATION IN POLYPEPTIDE SYNTHESIS.
    Proc Natl Acad Sci U S A. 1964 Jun;51:1291-9 PMID: 14215654
  19. Inhibition of protein synthesis in reticulocytes by antibiotics. II. The site of action of cycloheximide, streptovitacin A and pactamycin.
    Biochim Biophys Acta. 1966 Apr 18;119(1):120-9 PMID: 5960401
  20. ACTION OF INSULIN ON THE ISOLATED RAT DIAPHRAGM IN THE PRESENCE OF ACTINOMYCIN D AND PUROMYCIN.
    Nature. 1963 Sep 21;199:1183-4 PMID: 14072040
Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
DOI
10.1073/pnas.56.3.991
Published
1966-09-00
Pages
991-8
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC219959
Subset
IM
External Links
PubMed source DOI: 10.1073/pnas.56.3.991 PMC Full Text View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2