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PMID: 407163 Published · ppublish English Comparative Study Journal Article Research Support, U.S. Gov't, P.H.S.

Sucrose metabolism by prominent members of the flora isolated from cariogenic and non-cariogenic dental plaques.

Infection and immunity ·Vol. 17 ·No. 1 ·1977-07-00 ·Pages 55-61

Minah GE, Loesche WJ

Abstract

Sucrose metabolism by resting-cell suspensions of pure cultures of representative members of the predominant cultivable flora isolated from cariogenic and non-cariogenic dental plaque was investigated by means of radiochemical techniques. Streptocococcus mutans utilized sucrose at a considerably faster rate than S. sanguis, S. mitis, Actinomyces viscosus, A. naeslundii, or Lactobacillus casei, forming lactic acid, intracellular polysaccharide, insoluble extracellular glucan, and lactic acid from intracellular polysaccharide catabolism at faster rates than the other bacteria. The Actinomyces formed more volatile acids than the streptococci, mostly acetic, and S. sanguis formed more soluble extracellular polysaccharide than the other bacteria. The metabolic activity of S. mutans resembled the pattern of sucrose metabolism of cariogenic plaque, whereas the metabolic activity of the Actinomyces species, the predominant members of non-cariogenic plaque flora, resembled the sucrose metabolism of non-cariogenic plaques.

MeSH Terms
Actinomyces/metabolism Dental Caries/microbiology Dental Plaque/microbiology Fatty Acids, Volatile/metabolism Humans Lactates/metabolism Lactobacillus casei/metabolism Polysaccharides, Bacterial/metabolism Streptococcus/metabolism Streptococcus mutans/metabolism Streptococcus sanguis/metabolism Sucrose/metabolism
Chemicals
Fatty Acids, Volatile Lactates Polysaccharides, Bacterial Sucrose
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Minah G E
Loesche W J
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22 references, click to expand
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Article Info
Journal
Infection and immunity
Abbr.
Infect Immun
ISSN
0019-9567
DOI
10.1128/iai.17.1.55-61.1977
Published
1977-07-00
Pages
55-61
Language
English
Region
United States
NLM ID
0246127
PMCID
PMC421080
Subset
IM
External Links
PubMed source DOI: 10.1128/iai.17.1.55-61.1977 PMC Full Text View journal details
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