Home LiteratureArticle Details
PMID: 3896352 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S. Review

Cytogenetic and molecular biologic alterations in human breast cancer: a review.

Breast cancer research and treatment ·Vol. 5 ·No. 3 ·1985-00-00 ·Pages 221-9

Trent JM

Abstract

Chromosomal and molecular biologic studies of human breast cancer are beginning to provide insight into the basic biology of this important disease. The current state of knowledge of both cytogenetic evaluation and assessment of expression and amplification of cellular oncogenes in breast cancer will be outlined in this brief review.

MeSH Terms
Breast Neoplasms/genetics Chromosome Aberrations Chromosome Mapping Chromosomes, Human, 1-3 Chromosomes, Human, 6-12 and X Female Gene Amplification Humans Oncogenes
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Trent J M
References (28)
28 references, click to expand
  1. Break points in chromosome #1 abnormalities of 218 human neoplasms.
    Cancer Genet Cytogenet. 1981 Nov;4(3):215-25 PMID: 7317874
  2. Cytogenetic studies of human breast cancer lines: MCF-7 and derived variant sublines.
    J Natl Cancer Inst. 1983 Oct;71(4):687-95 PMID: 6578363
  3. Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells.
    Proc Natl Acad Sci U S A. 1982 Dec;79(24):7837-41 PMID: 6818551
  4. Generation of clonal variants in a human ovarian carcinoma studied by chromosome banding analysis.
    Cancer Genet Cytogenet. 1985 Jan 1;14(1-2):153-61 PMID: 3965120
  5. Expression of cellular oncogenes in human malignancies.
    Science. 1984 Apr 20;224(4646):256-62 PMID: 6538699
  6. Double minutes and homogeneously staining regions: gene amplification in mammalian cells.
    Annu Rev Genet. 1982;16:21-59 PMID: 6760799
  7. Human breast cancer in culture.
    Recent Results Cancer Res. 1976;(57):33-41 PMID: 1013510
  8. Karyotypic progression in human tumors.
    Cancer Metastasis Rev. 1983;2(3):257-93 PMID: 6231097
  9. Human immunoglobulin heavy chain genes map to a region of translocations in malignant B lymphocytes.
    Science. 1982 Apr 16;216(4543):301-3 PMID: 6801764
  10. The Fourth International Workshop on Chromosomes in Leukemia: a prospective study of acute nonlymphocytic leukemia. Chicago, Illinois, U.S.A., September 2-7, 1982.
    Cancer Genet Cytogenet. 1984 Mar;11(3):249-360 PMID: 6704928
  11. Amplification and expression of the c-myc oncogene in human lung cancer cell lines.
    Nature. 1983 Nov 10-16;306(5939):194-6 PMID: 6646201
  12. Chromosomes and causation of human cancer and leukemia. XIV. Origin of a large number of markers in a cancer.
    Cancer. 1976 Feb;37(2):776-82 PMID: 1253106
  13. A human cell line from a pleural effusion derived from a breast carcinoma.
    J Natl Cancer Inst. 1973 Nov;51(5):1409-16 PMID: 4357757
  14. Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells.
    Proc Natl Acad Sci U S A. 1982 Dec;79(24):7824-7 PMID: 6961453
  15. Varying degrees of amplification of the N-ras oncogene in the human breast cancer cell line MCF-7.
    Cancer Res. 1985 May;45(5):2201-5 PMID: 3986769
  16. [Comparative cytogenetic study of 7 types of mammary cancer].
    Ann Genet. 1977 Sep;20(3):171-7 PMID: 304700
  17. Catalogue of chromosome aberrations in cancer.
    Cytogenet Cell Genet. 1983;36(1-2):1-515 PMID: 6627995
  18. Cytogenetic analysis on eight human breast tumor cell lines: high frequencies of 1q, 11q and HeLa-like marker chromosomes.
    Cancer Genet Cytogenet. 1981 Jan;3(1):61-73 PMID: 7272986
  19. Bioactivities, estrogen receptor interactions, and plasminogen activator-inducing activities of tamoxifen and hydroxy-tamoxifen isomers in MCF-7 human breast cancer cells.
    Cancer Res. 1984 Jan;44(1):112-9 PMID: 6537799
  20. Preferential involvement of chromosome 1q in a primary breast carcinoma.
    Cancer Genet Cytogenet. 1981 Mar;3(2):125-9 PMID: 7272991
  21. Chromosomal sublocalization of human c-myb and c-fes cellular onc genes.
    Nature. 1983 Jul 14-20;304(5922):169-71 PMID: 6866112
  22. Characterization of an established cell line (SH-3) derived from pleural effusion of patient with breast cancer.
    Cancer. 1976 Apr;37(4):1814-24 PMID: 1260689
  23. Correlation between immunoglobulin light chain expression and variant translocation in Burkitt's lymphoma.
    Nature. 1982 Jul 29;298(5873):474-6 PMID: 6806672
  24. Cellular oncogenes and retroviruses.
    Annu Rev Biochem. 1983;52:301-54 PMID: 6351725
  25. Transcriptional activation of the translocated c-myc oncogene in burkitt lymphoma.
    Proc Natl Acad Sci U S A. 1983 Feb;80(3):820-4 PMID: 6402776
  26. Chromosome 6q involvement in human malignant melanoma.
    Cancer Genet Cytogenet. 1983 Jun;9(2):177-80 PMID: 6850557
  27. Karyotypic analysis of human ovarian carcinoma cells cloned in short term agar culture.
    Cancer Genet Cytogenet. 1981 Jun;3(4):279-91 PMID: 7260887
  28. Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour.
    Nature. 1983 Sep 15-21;305(5931):245-8 PMID: 6888561
Article Info
Journal
Breast cancer research and treatment
Abbr.
Breast Cancer Res Treat
ISSN
0167-6806
Published
1985-00-00
Pages
221-9
Language
English
Region
Netherlands
NLM ID
8111104
Subset
IM
Grants
NCI NIH HHS · CA-17094 · United States
NCI NIH HHS · CA-29476 · United States
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com