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PMID: 3891732 Published · ppublish English Journal Article

Recycling of murein by Escherichia coli.

Journal of bacteriology ·Vol. 163 ·No. 1 ·1985-07-00 ·Pages 305-10

Goodell EW

Abstract

The tripeptide (L-Ala-D-Glu-meso-diaminopimelic acid [A2pm]), tetrapeptide (L-Ala-D-Glu-A2pm-D-Ala), and dipeptide (A2pm-D-Ala) which are shed by Escherichia coli from the murein sacculus were found to be reused by the cells to synthesize murein. The tripeptide was used directly, without degradation, to form UDP-N-acetylmuramyl-L-Ala-D-Glu-A2pm. The tetrapeptide lost its carboxy-terminal D-Ala, apparently in the periplasm, before being used. The dipeptide was degraded to D-Ala and A2pm before uptake.

MeSH Terms
Biological Transport Escherichia coli/metabolism Glycopeptides/metabolism Kinetics Oligopeptides/metabolism Peptidoglycan/metabolism
Chemicals
Glycopeptides Oligopeptides Peptidoglycan
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Goodell E W
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25 references, click to expand
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Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/jb.163.1.305-310.1985
Published
1985-07-00
Pages
305-10
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC219113
Subset
IM
External Links
PubMed source DOI: 10.1128/jb.163.1.305-310.1985 PMC Full Text View journal details
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