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PMID: 388438 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Yeast chromatin is uniformly digested by DNase-I.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 76 ·No. 9 ·1979-09-00 ·Pages 4285-8

Lohr D, Hereford L

Abstract

The DNase I (EC 3.1.21.1) sensitivity of transcribed yeast chromatin has been examined. We find that, in contrast to chromatin from higher eukaryotes, transcribed yeast chromatin and total yeast chromatin are equally sensitive to DNase I digestion. We interpret these results to mean that the entire yeast genome exists in a state that represents a restricted proportion of total chromatin in higher eukaryotes.

MeSH Terms
Chromatin/metabolism DNA, Fungal/genetics,metabolism Deoxyribonucleases/metabolism Kinetics Nucleic Acid Hybridization Saccharomyces cerevisiae/genetics,metabolism Transcription, Genetic
Chemicals
Chromatin DNA, Fungal Deoxyribonucleases
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Lohr D
Hereford L
References (38)
38 references, click to expand
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Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
DOI
10.1073/pnas.76.9.4285
Published
1979-09-00
Pages
4285-8
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC411558
Subset
IM
External Links
PubMed source DOI: 10.1073/pnas.76.9.4285 PMC Full Text View journal details
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