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PMID: 3856871 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Expression of a mouse long terminal repeat is cell cycle-linked.

Augenlicht LH, Halsey H

Abstract

The expression of the long terminal repeat (LTR) of intracisternal A particle retroviral sequences which are endogenous to the mouse genome has been shown to be linked to the early G1 phase of the cell cycle in Friend erythroleukemia cells synchronized by density arrest and also in logarithmically growing cells fractionated into cell-cycle compartments by centrifugal elutriation. Regions of homology were found in comparing the LTR sequence to a repetitive Syrian hamster sequence specifically expressed in early G1 in hamster cells.

MeSH Terms
Animals Base Sequence Cell Cycle Cricetinae DNA, Neoplasm/analysis Friend murine leukemia virus Genes, Viral Leukemia, Erythroblastic, Acute/genetics Leukemia, Experimental/genetics Mesocricetus Mice Retroviridae/genetics Transcription, Genetic
Chemicals
DNA, Neoplasm
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Augenlicht L H
Halsey H
References (41)
41 references, click to expand
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Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
Published
1985-04-00
Pages
1946-9
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC397454
Subset
IM
Grants
NCI NIH HHS · CA 37381 · United States
NCI NIH HHS · CA 37487 · United States
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