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PMID: 3752994 Published · ppublish English Comparative Study Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Effects of microcosm salinity and organic substrate concentration on production of Vibrio cholerae enterotoxin.

Applied and environmental microbiology ·Vol. 52 ·No. 2 ·1986-08-00 ·Pages 297-301

Tamplin ML, Colwell RR

Abstract

The effects of aquatic processes on production of cholera toxin by Vibrio cholerae were studied with seawater microcosms. Several salinity and organic nutrient concentrations were employed. At 10 g of organic nutrient per liter of seawater, toxin production increased as the salinity was increased. At lower organic nutrient concentrations, toxin production was markedly enhanced when the salinity was 20 and 25%. Toxin concentration increased with salinity, independent of cell concentration and toxin stability. From the results obtained in this study, it is concluded that physical and chemical parameters of the aquatic environment affect not only the physiological state of V. cholerae, but also its potential pathogenicity.

MeSH Terms
Culture Media Enterotoxins/biosynthesis Kinetics Osmolar Concentration Seawater Species Specificity Vibrio cholerae/metabolism
Chemicals
Culture Media Enterotoxins stN protein, Vibrio cholerae
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Tamplin M L
Colwell R R
References (15)
15 references, click to expand
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Article Info
Journal
Applied and environmental microbiology
Abbr.
Appl Environ Microbiol
ISSN
0099-2240
DOI
10.1128/aem.52.2.297-301.1986
Published
1986-08-00
Pages
297-301
Language
English
Region
United States
NLM ID
7605801
PMCID
PMC203518
Subset
IM
Grants
PHS HHS · R22, A1-14242 · United States
External Links
PubMed source DOI: 10.1128/aem.52.2.297-301.1986 PMC Full Text View journal details
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