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PMID: 375198 Published · ppublish English Journal Article

Nucleotide sequence of the cro-cII-oop region of bacteriophage 434 DNA.

Nucleic acids research ·Vol. 6 ·No. 3 ·1979-03-00 ·Pages 867-81

Grosschedl R, Schwarz E

Abstract

The nucleotide sequence of a 869 bp segment of phage 434 DNA including the regulatory genes cro and cII is presented and compared with the corresponding part of the phage lambda DNA sequence. The 434 cro protein as deduced from the DNA sequence is a highly basic protein of 71 amino acid residues with a calculated molecular weight of 8089. While the cro gene sequences of phage 434 and lambda DNA are very different, the nuleotide sequences to the right of the lambda imm434 boundary show differences only at 11 out of 512 positions. Nucleotide substitutions in the cII gene occur with one exception in the third positions of the respective codons and only one out of several DNA regulatory signals located in this region of the phage genomes is affected by these nucleotide substitutions.

MeSH Terms
Amino Acid Sequence Base Sequence Coliphages/analysis,metabolism DNA, Viral/metabolism Escherichia coli/analysis Genes, Viral Nucleic Acid Conformation Protein Biosynthesis Transcription, Genetic Viral Proteins/biosynthesis
Chemicals
DNA, Viral Viral Proteins
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Grosschedl R
Schwarz E
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39 references, click to expand
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Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
0305-1048
DOI
10.1093/nar/6.3.867
Published
1979-03-00
Pages
867-81
Language
English
Region
England
NLM ID
0411011
PMCID
PMC327739
Subset
IM
Databases
GENBANK
J02475
External Links
PubMed source DOI: 10.1093/nar/6.3.867 PMC Full Text View journal details
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