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PMID: 360170 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Apurinic endonucleases from Saccharomyces cerevisiae.

Nucleic acids research ·Vol. 5 ·No. 9 ·1978-09-00 ·Pages 3347-56

Armel PR, Wallace SS

Abstract

Three endonuclease activities have been partially purified from Saccharomyces cerevisiae on the basis of their activity against x-irradiated closed-circular supercoiled bacteriophage PM2 DNA. These endonucleases also nick apurinic DNA and two out of the three activities incise DNA UV-irradiated with high doses. The endonuclease activities have also been distinguished on the basis of their magnesium requirement and sensitivity to EDTA.

MeSH Terms
Apurinic Acid Deoxyribonucleases/isolation & purification Endonucleases/isolation & purification Saccharomyces cerevisiae/enzymology Substrate Specificity
Chemicals
Apurinic Acid Deoxyribonucleases Endonucleases
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Armel P R
Wallace S S
References (35)
35 references, click to expand
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Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
0305-1048
DOI
10.1093/nar/5.9.3347
Published
1978-09-00
Pages
3347-56
Language
English
Region
England
NLM ID
0411011
PMCID
PMC342254
Subset
IM
External Links
PubMed source DOI: 10.1093/nar/5.9.3347 PMC Full Text View journal details
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