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PMID: 331325 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S.

Immunohistochemical localization in rabbit brain of a peptide resembling the COOH-terminal octapeptide of cholecystokinin.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 74 ·No. 7 ·1977-07-00 ·Pages 3033-4

Straus E, Muller JE, Choi HS, Paronetto F, Yalow RS

Abstract

Immunohistochemical techniques were used to demonstrate the presence of a material resembling the COOH-terminal octapeptide of cholecystokinin in rabbit cerebral cortical neurons. Deep staining was seen in cell bodies throughout the cortical grey matter and diffusely in the subcortical white matter.

MeSH Terms

Animals Cerebral Cortex/metabolism Cholecystokinin/metabolism Immunoenzyme Techniques Nerve Tissue Proteins/metabolism Oligopeptides/metabolism Rabbits

Chemicals

Nerve Tissue Proteins Oligopeptides Cholecystokinin

Authors & Affiliations

5 authors, click to expand affiliations / ORCID

Straus E

Muller J E

Choi H S

Paronetto F

Yalow R S

References (6)

6 references, click to expand

An unidentified depressor substance in certain tissue extracts.
J Physiol. 1931 Jun 6;72(1):74-87 PMID: 16994201
Peptides and neuronal function.
Adv Biochem Psychopharmacol. 1976;15:193-210 PMID: 15415
Cholecystokinin and its COOH-terminal octapeptide in the pig brain.
Proc Natl Acad Sci U S A. 1977 Jul;74(7):3035-7 PMID: 268651
The unlabeled antibody enzyme method of immunohistochemistry: preparation and properties of soluble antigen-antibody complex (horseradish peroxidase-antihorseradish peroxidase) and its use in identification of spirochetes.
J Histochem Cytochem. 1970 May;18(5):315-33 PMID: 4192899
The effects of substance P and other peptides on spinal neurons of the frog.
Brain Res. 1974 Jan 18;65(3):397-410 PMID: 4153509
The hypothalamus in pituitary-thyroid regulation.
Recent Prog Horm Res. 1972;28:229-86 PMID: 4631619

Article Info

Journal

Proceedings of the National Academy of Sciences of the United States of America

Abbr.

Proc Natl Acad Sci U S A

ISSN

0027-8424

DOI

10.1073/pnas.74.7.3033

Published

1977-07-00

Pages

3033-4

Language

English

Region

United States

NLM ID

7505876

PMCID

PMC431396

Subset

External Links

PubMed source DOI: 10.1073/pnas.74.7.3033 PMC Full Text View journal details

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Immunohistochemical localization in rabbit brain of a peptide resembling the COOH-terminal octapeptide of cholecystokinin.

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