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PMID: 3301821 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

fhuC and fhuD genes for iron (III)-ferrichrome transport into Escherichia coli K-12.

Journal of bacteriology ·Vol. 169 ·No. 8 ·1987-08-00 ·Pages 3844-9

Coulton JW, Mason P, Allatt DD

Abstract

The nucleotide sequence for a 1,900-base-pair region of the Escherichia coli chromosome that includes the genes fhuC and fhuD was determined. Within this sequence are two open reading frames: nucleotides 127 to 921 and nucleotides 924 to 1811. These coding regions specify a FhuC protein with an Mr of 28,423 and a mature FhuD protein with an Mr of 29,610. The deduced amino acid sequence of FhuC shows extensive homology with those of components of some bacterial transport systems which are peripheral proteins of the cytoplasmic membrane. Because the FhuD protein contains a typical signal sequence of 30 amino acids at the amino terminus and displays characteristics of a soluble protein, it may be exported into the periplasm.

MeSH Terms
Amino Acid Sequence Bacterial Proteins/genetics,metabolism Base Sequence Biological Transport, Active Escherichia coli/genetics,metabolism Ferric Compounds/metabolism Ferrichrome/metabolism Genes, Bacterial Hydroxamic Acids/metabolism Membrane Proteins/genetics,metabolism
Chemicals
Bacterial Proteins Ferric Compounds Hydroxamic Acids Membrane Proteins Ferrichrome
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Coulton J W
Mason P
Allatt D D
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21 references, click to expand
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Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/jb.169.8.3844-3849.1987
Published
1987-08-00
Pages
3844-9
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC212480
Subset
IM
Databases
GENBANK
M19210
External Links
PubMed source DOI: 10.1128/jb.169.8.3844-3849.1987 PMC Full Text View journal details
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