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PMID: 3132094 Published · ppublish English Journal Article

Plasmids and pheromone response of the beta-lactamase producer Streptococcus (Enterococcus) faecalis HH22.

Antimicrobial agents and chemotherapy ·Vol. 32 ·No. 4 ·1988-04-00 ·Pages 547-51

Murray BE, An FY, Clewell DB

Abstract

Streptococcus (Enterococcus) faecalis HH22 is a clinical isolate that produces beta-lactamase and is resistant to various other antimicrobial agents. In this study, HH22 was found to contain three conjugative plasmids and a conjugative transposon. pBEM10 encodes beta-lactamase, gentamicin resistance, and a response to the peptide pheromone cAD1; pAM323 encodes erythromycin resistance; and pAM324 encodes no known resistance. The latter two plasmids respond to pheromones designated cAM323 and cAM324 which are unrelated to other previously characterized pheromones. pBEM10 and pAM323 are the second and third examples of naturally occurring R plasmids that confer a sex pheromone response.

MeSH Terms
Conjugation, Genetic Enterococcus faecalis/drug effects,genetics Phenotype Pheromones/pharmacology R Factors/drug effects Sex Attractants/pharmacology Tetracycline Resistance/genetics Transformation, Bacterial
Chemicals
Pheromones Sex Attractants
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Murray B E
Department of Medicine, University of Texas Medical School, Houston 77030.
An F Y
Clewell D B
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Article Info
Journal
Antimicrobial agents and chemotherapy
Abbr.
Antimicrob Agents Chemother
ISSN
0066-4804
DOI
10.1128/AAC.32.4.547
Published
1988-04-00
Pages
547-51
Language
English
Region
United States
NLM ID
0315061
PMCID
PMC172218
Subset
IM
External Links
PubMed source DOI: 10.1128/AAC.32.4.547 PMC Full Text View journal details
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