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PMID: 3029419 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Complete interaction of cellular 56,000- and 32,000-Mr proteins with simian virus 40 small-t antigen in productively infected cells.

Journal of virology ·Vol. 61 ·No. 4 ·1987-04-00 ·Pages 1240-3

Rundell K

Abstract

Two cellular proteins are found to be complexed with simian virus 40 small-t antigen in cellular extracts. The complex is a relatively unstable but dynamic one which can dissociate and reform in extracts. In extracts of permissive monkey kidney cells, the small-t antigen appeared to be present in excess, whereas the cellular proteins were nearly entirely committed to the complex in permissive monkey kidney cells.

MeSH Terms
Animals Antigens, Polyomavirus Transforming Antigens, Viral, Tumor/metabolism Cell Line Cell Transformation, Viral Chlorocebus aethiops Macromolecular Substances Molecular Weight Oncogene Proteins, Viral/metabolism Protein Kinases/metabolism Proteins/isolation & purification,metabolism Simian virus 40/genetics
Chemicals
Antigens, Polyomavirus Transforming Antigens, Viral, Tumor Macromolecular Substances Oncogene Proteins, Viral Proteins Protein Kinases
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Rundell K
References (17)
17 references, click to expand
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Article Info
Journal
Journal of virology
Abbr.
J Virol
ISSN
0022-538X
DOI
10.1128/JVI.61.4.1240-1243.1987
Published
1987-04-00
Pages
1240-3
Language
English
Region
United States
NLM ID
0113724
PMCID
PMC254086
Subset
IM
Grants
NCI NIH HHS · CA21327 · United States
External Links
PubMed source DOI: 10.1128/JVI.61.4.1240-1243.1987 PMC Full Text View journal details
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