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PMID: 3003370 Published · ppublish English Comparative Study Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Evolution of Alu family repeats since the divergence of human and chimpanzee.

Journal of molecular evolution ·Vol. 22 ·No. 4 ·1985-00-00 ·Pages 316-22

Sawada I, Willard C, Shen CK, Chapman B, Wilson AC, Schmid CW

Abstract

The DNA sequences of three members of the Alu family of repeated sequences located 5' to the chimpanzee alpha 2 gene have been determined. The base sequences of the three corresponding human Alu family repeats have been previously determined, permitting the comparison of identical Alu family members in human and chimpanzee. Here we compare the sequences of seven pairs of chimpanzee and human Alu repeats. In each case, with the exception of minor sequence differences, the identical Alu repeat is located at identical sites in the human and chimpanzee genomes. The Alu repeats diverge at the rate expected for nonselected sequences. Sequence conversion has not replaced any of these 14 Alu family members since the divergence between chimpanzee and human.

MeSH Terms
Animals Base Sequence Biological Evolution DNA Restriction Enzymes Genes Genetic Variation Globins/genetics Humans Pan troglodytes Repetitive Sequences, Nucleic Acid Species Specificity
Chemicals
Globins DNA Restriction Enzymes
Authors & Affiliations
6 authors, click to expand affiliations / ORCID
Sawada I
Willard C
Shen C K
Chapman B
Wilson A C
Schmid C W
References (33)
33 references, click to expand
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Article Info
Journal
Journal of molecular evolution
Abbr.
J Mol Evol
ISSN
0022-2844
DOI
10.1007/BF02115687
Published
1985-00-00
Pages
316-22
Language
English
Region
Germany
NLM ID
0360051
Subset
IM
Grants
NIADDK NIH HHS · AM 29800 · United States
NIGMS NIH HHS · GM 21346 · United States
Databases
GENBANK
X03275, X03276
External Links
PubMed source DOI: 10.1007/BF02115687 View journal details
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