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PMID: 2985829 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Shutoff of host translation by encephalomyocarditis virus infection does not involve cleavage of the eucaryotic initiation factor 4F polypeptide that accompanies poliovirus infection.

Journal of virology ·Vol. 54 ·No. 2 ·1985-05-00 ·Pages 643-5

Mosenkis J, Daniels-McQueen S, Janovec S, Duncan R, Hershey JW, Grifo JA, Merrick WC, Thach RE

Abstract

Studies were conducted to determine whether encephalomyocarditis virus infection causes proteolytic cleavage of any of the polypeptides which comprise eucaryotic initiation factor 4F. Since no such alterations in the components of the initiation factor were detected, these observations confirmed that the mechanisms whereby encephalomyocarditis virus and poliovirus shut off host translation are different.

MeSH Terms
Animals Encephalomyocarditis virus/genetics Eukaryotic Initiation Factor-4F L Cells Peptide Initiation Factors/metabolism Poliovirus/genetics Protein Biosynthesis
Chemicals
Eukaryotic Initiation Factor-4F Peptide Initiation Factors
Authors & Affiliations
8 authors, click to expand affiliations / ORCID
Mosenkis J
Daniels-McQueen S
Janovec S
Duncan R
Hershey J W
Grifo J A
Merrick W C
Thach R E
References (18)
18 references, click to expand
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Article Info
Journal
Journal of virology
Abbr.
J Virol
ISSN
0022-538X
DOI
10.1128/JVI.54.2.643-645.1985
Published
1985-05-00
Pages
643-5
Language
English
Region
United States
NLM ID
0113724
PMCID
PMC254842
Subset
IM
Grants
NIAID NIH HHS · AI 20484 · United States
NIGMS NIH HHS · GM 07250 · United States
NIGMS NIH HHS · GM 26796 · United States
External Links
PubMed source DOI: 10.1128/JVI.54.2.643-645.1985 PMC Full Text View journal details
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