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PMID: 2901348 Published · ppublish English Comparative Study Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

A novel, tissue-specific, Drosophila homeobox gene.

The EMBO journal ·Vol. 7 ·No. 7 ·1988-07-00 ·Pages 2151-61

Barad M, Jack T, Chadwick R, McGinnis W

Abstract

The homeobox gene family of Drosophila appears to control a variety of position-specific patterning decisions during embryonic and imaginal development. Most of these patterning decisions determine groups of cells on the anterior-posterior axis of the Drosophila germ band. We have isolated a novel homeobox gene from Drosophila, designated H2.0. H2.0 has the most diverged homeobox so far characterized in metazoa, and, in contrast to all previously isolated homeobox genes, H2.0 exhibits a tissue-specific pattern of expression. The cells that accumulate transcripts for this novel gene correspond to the visceral musculature and its anlagen.

MeSH Terms
Amino Acid Sequence Animals Base Sequence Biological Evolution DNA/genetics,isolation & purification DNA Restriction Enzymes Drosophila/embryology,genetics Embryo, Nonmammalian/physiology Genes, Homeobox Humans Molecular Sequence Data Organ Specificity Species Specificity Transcription, Genetic
Chemicals
DNA DNA Restriction Enzymes
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Barad M
Department of Human Genetics, Yale University, New Haven, Connecticut 06511.
Jack T
Chadwick R
McGinnis W
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Article Info
Journal
The EMBO journal
Abbr.
EMBO J
ISSN
0261-4189
Published
1988-07-00
Pages
2151-61
Language
English
Region
England
NLM ID
8208664
PMCID
PMC454523
Subset
IM
Grants
NIGMS NIH HHS · GM07205 · United States
Databases
GENBANK
Y00843
External Links
PubMed source PMC Full Text View journal details
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