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PMID: 3014511 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Homeo box gene expression in anterior and posterior regions of the Drosophila embryo.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 83 ·No. 13 ·1986-07-00 ·Pages 4809-13

Hoey T, Doyle HJ, Harding K, Wedeen C, Levine M

Abstract

The homeo box is a 180-base-pair coding sequence that has been implicated in the control of Drosophila development. A common feature of the nine previously reported homeo box genes is their involvement in the establishment of the segmentation pattern of the embryo. In this report we describe the isolation and properties of two additional homeo box genes, F90-2 and S67. Transcripts encoded by the two genes are detected in embryonic tissues that derive from regions near the anterior and posterior poles of the embryo, which are outside the limits of expression of known homeotic genes. These results suggest that at least some homeo box genes specify positional identity along the anterior-posterior body axis that is independent of the process of segmentation.

MeSH Terms
Amino Acid Sequence Animals Base Sequence Chromosome Mapping Cloning, Molecular DNA Restriction Enzymes Drosophila melanogaster/embryology,genetics Gene Expression Regulation Genes, Regulator Morphogenesis Nucleic Acid Hybridization RNA, Messenger/genetics Transcription, Genetic
Chemicals
RNA, Messenger DNA Restriction Enzymes
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Hoey T
Doyle H J
Harding K
Wedeen C
Levine M
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34 references, click to expand
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Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
DOI
10.1073/pnas.83.13.4809
Published
1986-07-00
Pages
4809-13
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC323831
Subset
IM
Databases
GENBANK
M13570
External Links
PubMed source DOI: 10.1073/pnas.83.13.4809 PMC Full Text View journal details
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