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PMID: 268629 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Isolation and identification of aliphatic short-chain acylcarnitines from beef heart: possible role for carnitine in branched-chain amino acid metabolism.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 74 ·No. 7 ·1977-07-00 ·Pages 2795-8

Bieber LL, Choi YR

Abstract

Aliphatic acylearnitines isolated from a water-soluble fraction of beef heart have been characterized by gas chromatography and mass spectrometry. The following acyl residues derived from the acylcarnitine fraction were unequivocally identified: acetyl, propionyl, isobutyryl, butyryl, alpha-methylbutyryl, valeryl, isovaleryl, tiglyl, and caproyl. beta-methylcrotonyl and methacrylyl were tentatively identified. This occurrence of considerable quantities of branched-chain acylcarnitines indicates a role for carnitine in branched-chain amino acid metabolism.

MeSH Terms
Amino Acids/metabolism Animals Carnitine/analogs & derivatives,analysis,metabolism Carnitine Acyltransferases/metabolism Cattle Mass Spectrometry Myocardium/analysis
Chemicals
Amino Acids Carnitine Acyltransferases Carnitine
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Bieber L L
Choi Y R
References (31)
31 references, click to expand
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Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
DOI
10.1073/pnas.74.7.2795
Published
1977-07-00
Pages
2795-8
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC431294
Subset
IM
External Links
PubMed source DOI: 10.1073/pnas.74.7.2795 PMC Full Text View journal details
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