A community outbreak of group A beta haemolytic streptococci with transferable resistance to erythromycin.

Epidemiology and infection ·Vol. 102 ·No. 1 ·1989-02-00 ·Pages 85-91

Scott RJ, Naidoo J, Lightfoot NF, George RC

Abstract

Erythromycin resistance amongst group A streptococci (GAS) in Great Britain is a relatively rare occurrence and outbreaks have been sporadically reported. Over an 8-month period in 1986 ten associated cases occurred in the town of Bridgewater in Somerset. Isolates were group A, type M4 and resistant to erythromycin (MIC 8 mg/l) but sensitive to lincomycin and clindamycin. Erythromycin resistance was transferable from all isolates to a group A recipient strain. No plasmid DNA could be detected in the original isolates or transconjugants.

MeSH Terms

Adult Child Child, Preschool Conjugation, Genetic Disease Outbreaks Drug Resistance, Microbial/genetics England Erythromycin/pharmacology Female Humans Infant Male Schools Streptococcal Infections/epidemiology,microbiology Streptococcus pyogenes/genetics,isolation & purification

Chemicals

Erythromycin

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Scott R J

Public Health Laboratory, Musgrove Park Hospital, Taunton, Somerset.

Naidoo J

Lightfoot N F

George R C

References (14)

14 references, click to expand

Erythromycin resistant Streptococcus pyogenes in Cambridge.
J Infect. 1984 Jan;8(1):88-9 PMID: 6366072
Erythromycin-resistant beta-haemolytic streptococci in North Yorkshire.
J Infect. 1986 Sep;13(2):200-2 PMID: 3760601
Sensitivity of group A streptococci to antibiotics. Prevalence of resistance to erythromycin in Japan.
Am J Dis Child. 1979 Nov;133(11):1143-5 PMID: 389035
Erythromycin resistant Streptococcus pyogenes in Merseyside.
J Infect. 1984 Jan;8(1):86-7 PMID: 6366071
Narrow host range of some streptococcal R plasmids.
Plasmid. 1982 Sep;8(2):199-206 PMID: 7178293
Susceptibility of group A beta-hemolytic Streptococcus isolates to penicillin and erythromycin.
Antimicrob Agents Chemother. 1981 Aug;20(2):244-6 PMID: 7025754
Transfer of erythromycin resistance from clinically isolated lysogenic strains of Streptococcus pyogenes via their endogenous phage.
J Infect Dis. 1978 Sep;138(3):281-6 PMID: 359722
Translocation of antibiotic resistance markers of a plasmid-free Streptococcus pyogenes (group A) strain into different streptococcal hemolysin plasmids.
Mol Gen Genet. 1984;194(3):377-87 PMID: 6330497
Characterization of a plasmid determining resistance to erythromycin, lincomycin, and vernamycin Balpha in a strain Streptococcus pyogenes.
Antimicrob Agents Chemother. 1974 May;5(5):534-7 PMID: 4618462
Group A streptococci resistant to lincomycin.
Br Med J. 1968 Mar 16;1(5593):703 PMID: 4867862
Plasmid content of Streptococcus faecalis strain 39-5 and identification of a pheromone (cPD1)-induced surface antigen.
J Gen Microbiol. 1983 Apr;129(4):1207-15 PMID: 6411857
Conjugative transposons and the dissemination of antibiotic resistance in streptococci.
Annu Rev Microbiol. 1986;40:635-59 PMID: 3022640
The sensitivity of staphylococci and other wound bacteria to erythromycin, oleandomycin, and spiramycin.
J Clin Pathol. 1959 Mar;12(2):163-9 PMID: 13641436
Conjugative transfer of multiple-antibiotic resistance markers in beta-hemolytic group A, B, F, and G streptococci in the absence of extrachromosomal deoxyribonucleic acid.
Plasmid. 1981 Mar;5(2):127-37 PMID: 6264518

Article Info

Journal

Epidemiology and infection

Abbr.

Epidemiol Infect

ISSN

0950-2688

DOI

10.1017/s095026880002971x

Published

1989-02-00

Pages

85-91

Language

English

Region

England

NLM ID

8703737

PMCID

PMC2249306

Subset

External Links

PubMed source DOI: 10.1017/s095026880002971x PMC Full Text View journal details

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A community outbreak of group A beta haemolytic streptococci with transferable resistance to erythromycin.

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