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PMID: 25677994 Published · ppublish English Journal Article Review

Urinary tract infections in the infant.

Clinics in perinatology ·Vol. 42 ·No. 1 ·2015-03-00 ·Pages 17-28, vii

Arshad M, Seed PC

Abstract

Urinary tract infection (UTI) in an infant may be the first indication of an underlying renal disorder. Early recognition and initiation of adequate therapy for UTI is important to reduce the risk of long-term renal scarring. Ampicillin and gentamicin are traditionally the empiric treatment of choice; however, local antibiotic resistance patterns should be considered. Maternal antibiotics during pregnancy also increase the risk of resistant pathogens during neonatal UTI. Long-term management after the first UTI in infants remains controversial because of lack of specific studies in this age group and the risk-benefit issues for antibiotic prophylaxis between reduced recurrent disease and emergent antibiotic resistance.

Keywords
Antibiotic resistance Escherichia coli Infants Renal imaging Urinary tract infection Vesicoureteral reflux
MeSH Terms
Anti-Bacterial Agents/therapeutic use Antibiotic Prophylaxis Candidiasis/drug therapy,etiology Circumcision, Male Drug Resistance, Bacterial Escherichia coli Infections/drug therapy,etiology Female Humans Infant Infant, Newborn Infant, Premature Male Urinary Tract Infections/drug therapy,etiology,microbiology Urogenital Abnormalities/complications,diagnosis Vesico-Ureteral Reflux/complications,diagnosis
Chemicals
Anti-Bacterial Agents
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Arshad Mehreen
Division of Infectious Diseases, Department of Pediatrics, Duke University School of Medicine, DUMC 3499, Durham, NC 27710, USA.
Seed Patrick C
Division of Infectious Diseases, Department of Pediatrics, Duke University School of Medicine, DUMC 3499, Durham, NC 27710, USA. Electronic address: patrick.seed@duke.edu.
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Article Info
Journal
Clinics in perinatology
Abbr.
Clin Perinatol
ISSN
1557-9840
DOI
10.1016/j.clp.2014.10.003
Email
patrick.seed@duke.edu
Published
2015-03-00
Epub
2014-00-24
Pages
17-28, vii
Language
English
Region
United States
NLM ID
7501306
PMCID
PMC5511626
Subset
IM
Grants
NICHD NIH HHS · K12 HD000850 · United States
NICHD NIH HHS · K12 HD043494 · United States
External Links
PubMed source DOI: 10.1016/j.clp.2014.10.003 PMC Full Text View journal details
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